The early IL-6 and IL-10 response in trauma is correlated with injury severity and mortality

J Stensballe; M Christiansen; Else Kirstine Tønnesen; K Espersen; F K Lippert; L S Rasmussen

doi:10.1111/j.1399-6576.2008.01801.x

The early IL-6 and IL-10 response in trauma is correlated with injury severity and mortality

J Stensballe, M Christiansen, Else Kirstine Tønnesen, K Espersen, F K Lippert, L S Rasmussen

96 Citationer (Scopus)

Abstract

Trauma has previously been shown to influence interleukin (IL)-6 and IL-10 levels, but the association of injury severity and mortality with IL-6 and IL-10 responses in the early phase of accidental trauma remains to be investigated. We wished to describe serum levels of IL-6 and IL-10 in the first 24 h after trauma and to assess the relationship with severity of injury and mortality.

Originalsprog	Engelsk
Tidsskrift	Acta Anaesthesiologica Scandinavica
Vol/bind	53
Udgave nummer	4
Sider (fra-til)	515-21
Antal sider	7
ISSN	0001-5172
DOI	https://doi.org/10.1111/j.1399-6576.2008.01801.x
Status	Udgivet - apr. 2009

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abstract = "Trauma has previously been shown to influence interleukin (IL)-6 and IL-10 levels, but the association of injury severity and mortality with IL-6 and IL-10 responses in the early phase of accidental trauma remains to be investigated. We wished to describe serum levels of IL-6 and IL-10 in the first 24 h after trauma and to assess the relationship with severity of injury and mortality.",

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AU - Stensballe, J

AU - Christiansen, M

AU - Tønnesen, Else Kirstine

AU - Espersen, K

AU - Lippert, F K

AU - Rasmussen, L S

PY - 2009/4

Y1 - 2009/4

N2 - Trauma has previously been shown to influence interleukin (IL)-6 and IL-10 levels, but the association of injury severity and mortality with IL-6 and IL-10 responses in the early phase of accidental trauma remains to be investigated. We wished to describe serum levels of IL-6 and IL-10 in the first 24 h after trauma and to assess the relationship with severity of injury and mortality.

AB - Trauma has previously been shown to influence interleukin (IL)-6 and IL-10 levels, but the association of injury severity and mortality with IL-6 and IL-10 responses in the early phase of accidental trauma remains to be investigated. We wished to describe serum levels of IL-6 and IL-10 in the first 24 h after trauma and to assess the relationship with severity of injury and mortality.

KW - Adult

KW - Aged

KW - Female

KW - Humans

KW - Injury Severity Score

KW - Interleukin-10

KW - Interleukin-6

KW - Logistic Models

KW - Male

KW - Middle Aged

KW - Wounds and Injuries

UR - https://www.scopus.com/pages/publications/63149101598

U2 - 10.1111/j.1399-6576.2008.01801.x

DO - 10.1111/j.1399-6576.2008.01801.x

M3 - Journal article

C2 - 19317866

SN - 0001-5172

VL - 53

SP - 515

EP - 521

JO - Acta Anaesthesiologica Scandinavica

JF - Acta Anaesthesiologica Scandinavica

IS - 4

ER -

The early IL-6 and IL-10 response in trauma is correlated with injury severity and mortality

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