The cognitive effects of opioids in cancer: a systematic review

Geana Paula Kurita; Lena Lundorff; Cibele Andrucioli de Mattos Pimenta; Per Sjøgren

doi:10.1007/s00520-008-0497-y

The cognitive effects of opioids in cancer: a systematic review

Geana Paula Kurita, Lena Lundorff, Cibele Andrucioli de Mattos Pimenta, Per Sjøgren

44 Citationer (Scopus)

Abstract

OBJECTIVE AND METHODS: In order to better understand the effects of opioids on the cognitive function in cancer pain patients, a literature search was performed in PubMed, EMBASE, PsycInfo, CINAHL and Lilacs databases. Ten controlled trials were selected and classified according to the study design, the level of evidence, and opioid regimen.

RESULT: Six studies reported association between poor cognitive performance (reaction time, attention, balance, and memory) and opioid use.

CONCLUSION: These cognitive deficits were captured with neuropsychological tests; however, their clinical relevance is still uncertain.

Originalsprog	Engelsk
Tidsskrift	Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Vol/bind	17
Udgave nummer	1
Sider (fra-til)	11-21
Antal sider	11
ISSN	0941-4355
DOI	https://doi.org/10.1007/s00520-008-0497-y
Status	Udgivet - jan. 2009

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title = "The cognitive effects of opioids in cancer: a systematic review",

abstract = "OBJECTIVE AND METHODS: In order to better understand the effects of opioids on the cognitive function in cancer pain patients, a literature search was performed in PubMed, EMBASE, PsycInfo, CINAHL and Lilacs databases. Ten controlled trials were selected and classified according to the study design, the level of evidence, and opioid regimen.RESULT: Six studies reported association between poor cognitive performance (reaction time, attention, balance, and memory) and opioid use.CONCLUSION: These cognitive deficits were captured with neuropsychological tests; however, their clinical relevance is still uncertain.",

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AU - Lundorff, Lena

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AU - Sjøgren, Per

PY - 2009/1

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KW - Neoplasms/complications

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KW - Pain/drug therapy

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The cognitive effects of opioids in cancer: a systematic review

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