The association of polymorphisms in 5-fluorouracil metabolism genes with outcome in adjuvant treatment of colorectal cancer

Afzal Shoaib; Milena Gusella; Søren Astrup Jensen; Ben Vainer; Ulla Birgitte Vogel; Jon Trærup Andersen; Kasper Brødbæk; Morten Petersen; Espen Jimenez-Solem; Vilmos Adleff; Barna Budai; Erika Hitre; István Láng; Eniko Orosz; Laura Bertolaso; Carmen Barile; Roberto Padrini; Judit Kralovánszky; Felice Pasini; Henrik Enghusen Poulsen

doi:10.2217/pgs.11.83

The association of polymorphisms in 5-fluorouracil metabolism genes with outcome in adjuvant treatment of colorectal cancer

Afzal Shoaib, Milena Gusella, Søren Astrup Jensen, Ben Vainer, Ulla Birgitte Vogel, Jon Trærup Andersen, Kasper Brødbæk, Morten Petersen, Espen Jimenez-Solem, Vilmos Adleff, Barna Budai, Erika Hitre, István Láng, Eniko Orosz, Laura Bertolaso, Carmen Barile, Roberto Padrini, Judit Kralovánszky, Felice Pasini, Henrik Enghusen Poulsen

32 Citationer (Scopus)

Abstract

The purpose of this study was to investigate whether specific combinations of polymorphisms in 5-fluorouracil (5-FU) metabolism-related genes were associated with outcome in 5-FU-based adjuvant treatment of colorectal cancer.

Originalsprog	Engelsk
Tidsskrift	Pharmacogenomics
Vol/bind	12
Udgave nummer	9
Sider (fra-til)	1257-67
Antal sider	11
ISSN	1462-2416
DOI	https://doi.org/10.2217/pgs.11.83
Status	Udgivet - 2011

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10.2217/pgs.11.83

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Shoaib, A., Gusella, M., Jensen, S. A., Vainer, B., Vogel, U. B., Andersen, J. T., Brødbæk, K., Petersen, M., Jimenez-Solem, E., Adleff, V., Budai, B., Hitre, E., Láng, I., Orosz, E., Bertolaso, L., Barile, C., Padrini, R., Kralovánszky, J., Pasini, F., & Poulsen, H. E. (2011). The association of polymorphisms in 5-fluorouracil metabolism genes with outcome in adjuvant treatment of colorectal cancer. Pharmacogenomics, 12(9), 1257-67. https://doi.org/10.2217/pgs.11.83

Shoaib, A, Gusella, M, Jensen, SA, Vainer, B, Vogel, UB, Andersen, JT, Brødbæk, K, Petersen, M, Jimenez-Solem, E, Adleff, V, Budai, B, Hitre, E, Láng, I, Orosz, E, Bertolaso, L, Barile, C, Padrini, R, Kralovánszky, J, Pasini, F & Poulsen, HE 2011, 'The association of polymorphisms in 5-fluorouracil metabolism genes with outcome in adjuvant treatment of colorectal cancer', Pharmacogenomics, bind 12, nr. 9, s. 1257-67. https://doi.org/10.2217/pgs.11.83

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title = "The association of polymorphisms in 5-fluorouracil metabolism genes with outcome in adjuvant treatment of colorectal cancer",

abstract = "The purpose of this study was to investigate whether specific combinations of polymorphisms in 5-fluorouracil (5-FU) metabolism-related genes were associated with outcome in 5-FU-based adjuvant treatment of colorectal cancer.",

author = "Afzal Shoaib and Milena Gusella and Jensen, {S{\o}ren Astrup} and Ben Vainer and Vogel, {Ulla Birgitte} and Andersen, {Jon Tr{\ae}rup} and Kasper Br{\o}db{\ae}k and Morten Petersen and Espen Jimenez-Solem and Vilmos Adleff and Barna Budai and Erika Hitre and Istv{\'a}n L{\'a}ng and Eniko Orosz and Laura Bertolaso and Carmen Barile and Roberto Padrini and Judit Kralov{\'a}nszky and Felice Pasini and Poulsen, {Henrik Enghusen}",

year = "2011",

doi = "10.2217/pgs.11.83",

language = "English",

volume = "12",

pages = "1257--67",

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T1 - The association of polymorphisms in 5-fluorouracil metabolism genes with outcome in adjuvant treatment of colorectal cancer

AU - Shoaib, Afzal

AU - Gusella, Milena

AU - Jensen, Søren Astrup

AU - Vainer, Ben

AU - Vogel, Ulla Birgitte

AU - Andersen, Jon Trærup

AU - Brødbæk, Kasper

AU - Petersen, Morten

AU - Jimenez-Solem, Espen

AU - Adleff, Vilmos

AU - Budai, Barna

AU - Hitre, Erika

AU - Láng, István

AU - Orosz, Eniko

AU - Bertolaso, Laura

AU - Barile, Carmen

AU - Padrini, Roberto

AU - Kralovánszky, Judit

AU - Pasini, Felice

AU - Poulsen, Henrik Enghusen

PY - 2011

Y1 - 2011

N2 - The purpose of this study was to investigate whether specific combinations of polymorphisms in 5-fluorouracil (5-FU) metabolism-related genes were associated with outcome in 5-FU-based adjuvant treatment of colorectal cancer.

AB - The purpose of this study was to investigate whether specific combinations of polymorphisms in 5-fluorouracil (5-FU) metabolism-related genes were associated with outcome in 5-FU-based adjuvant treatment of colorectal cancer.

U2 - 10.2217/pgs.11.83

DO - 10.2217/pgs.11.83

M3 - Journal article

C2 - 21919605

SN - 1462-2416

VL - 12

SP - 1257

EP - 1267

JO - Pharmacogenomics

JF - Pharmacogenomics

IS - 9

ER -

The association of polymorphisms in 5-fluorouracil metabolism genes with outcome in adjuvant treatment of colorectal cancer

Abstract

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