TY - JOUR
T1 - The Association between Sleep Problems and Neuropsychological Deficits in Medication-naïve Children with ADHD
AU - Lambek, Rikke
AU - Thomsen, Per Hove
AU - Sonuga-Barke, Edmund J S
AU - Jennum, Poul
AU - Sørensen, Anne Virring
PY - 2022
Y1 - 2022
N2 - Background: Children with ADHD are reported to have sleep problems and neuropsychological deficits, but studies examining a potential association between the two are scarce and the use of varying methodology can complicate conclusions.Participants: A clinical sample of 59 medication-naïve children with ADHD between the ages of 6 and 14 years (71% male).Methods: Children underwent polysomnography and multiple sleep latency test, and parent rated sleep habits on the Children's Sleep Habits Questionnaire. Children also completed an extensive neuropsychological battery of executive function and delay aversion tasks, and parents and teachers rated executive function behavior on the Behavior Rating Inventory of Executive Function. Linear regression analyses were conducted with each of the neuropsychological outcomes included as the outcome variable and the sleep parameters as the predictor variables.Results: The correlations between sleep and neuropsychological outcomes were generally modest, but some sleep parameters (primarily sleep stages and sleep latencies) were associated with objectively and subjectively measured executive function and delay aversion.Conclusions: Using objective and subjective gold standard assessment procedures this study supports a (modest) association between sleep and neuropsychological function in children with ADHD.
AB - Background: Children with ADHD are reported to have sleep problems and neuropsychological deficits, but studies examining a potential association between the two are scarce and the use of varying methodology can complicate conclusions.Participants: A clinical sample of 59 medication-naïve children with ADHD between the ages of 6 and 14 years (71% male).Methods: Children underwent polysomnography and multiple sleep latency test, and parent rated sleep habits on the Children's Sleep Habits Questionnaire. Children also completed an extensive neuropsychological battery of executive function and delay aversion tasks, and parents and teachers rated executive function behavior on the Behavior Rating Inventory of Executive Function. Linear regression analyses were conducted with each of the neuropsychological outcomes included as the outcome variable and the sleep parameters as the predictor variables.Results: The correlations between sleep and neuropsychological outcomes were generally modest, but some sleep parameters (primarily sleep stages and sleep latencies) were associated with objectively and subjectively measured executive function and delay aversion.Conclusions: Using objective and subjective gold standard assessment procedures this study supports a (modest) association between sleep and neuropsychological function in children with ADHD.
KW - Adolescent
KW - Attention Deficit Disorder with Hyperactivity
KW - Child
KW - Female
KW - Humans
KW - Male
KW - Neuropsychological Tests
KW - Polysomnography/methods
KW - Sleep
KW - Sleep Wake Disorders/psychology
KW - Surveys and Questionnaires
UR - http://www.scopus.com/inward/record.url?scp=85107508105&partnerID=8YFLogxK
U2 - 10.1080/15402002.2021.1931222
DO - 10.1080/15402002.2021.1931222
M3 - Journal article
C2 - 34081546
SN - 1540-2002
VL - 20
SP - 429
EP - 441
JO - Behavioral sleep medicine
JF - Behavioral sleep medicine
IS - 4
ER -