The Angioarchitecture of the Optic Nerve Head in Patients with Optic Disc Drusen

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Region Hovedstaden - en del af Københavns Universitetshospital

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Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Author

Vahlgren, Julie ; Malmqvist, Lasse ; Rueløkke, Lea Lybæk ; Karlesand, Isabelle ; Lindberg, Anne Sofie Wessel ; Hamann, Steffen. / The Angioarchitecture of the Optic Nerve Head in Patients with Optic Disc Drusen. I: Neuro-Ophthalmology. 2020 ; Bind 44, Nr. 1. s. 5-10.

Bibtex

@article{9e6b0b3492ae44d0a4a847035934d5e0,

title = "The Angioarchitecture of the Optic Nerve Head in Patients with Optic Disc Drusen",

abstract = "The aim was to analyse the optic disc angioarchitecture in optic disc drusen (ODD) patients using computer-based fundus analysis in a case–control study. Compared with controls the ODD group had a significantly more centralised central retinal artery (CRA) emergence (p < 0.001) and primary CRA branching (p = 0.008), a higher number of CRA bifurcations (p = 0.02), a larger vertical optic disc diameter (p = 0.02) and a smaller cup/disc ratio (p < 0.001). The CRA emergence was largely within the nasal zone for both groups. The distinctive angioarchitecture of the optic disc in ODD patients can play a role in understanding the pathogenic cause of ODD.",

keywords = "Optic disc drusen, optic nerve head angioarchitecture, optic nerve head drusen, optic nerve head microvasculature",

author = "Julie Vahlgren and Lasse Malmqvist and Ruel{\o}kke, {Lea Lyb{\ae}k} and Isabelle Karlesand and Lindberg, {Anne Sofie Wessel} and Steffen Hamann",

year = "2020",

month = "1",

day = "2",

doi = "10.1080/01658107.2019.1613666",

language = "English",

volume = "44",

pages = "5--10",

journal = "Neuro-Ophthalmology",

issn = "0077-7803",

publisher = "C.V.Mosby Co.",

number = "1",

}

RIS

TY - JOUR

T1 - The Angioarchitecture of the Optic Nerve Head in Patients with Optic Disc Drusen

AU - Vahlgren, Julie

AU - Malmqvist, Lasse

AU - Rueløkke, Lea Lybæk

AU - Karlesand, Isabelle

AU - Lindberg, Anne Sofie Wessel

AU - Hamann, Steffen

PY - 2020/1/2

Y1 - 2020/1/2

N2 - The aim was to analyse the optic disc angioarchitecture in optic disc drusen (ODD) patients using computer-based fundus analysis in a case–control study. Compared with controls the ODD group had a significantly more centralised central retinal artery (CRA) emergence (p < 0.001) and primary CRA branching (p = 0.008), a higher number of CRA bifurcations (p = 0.02), a larger vertical optic disc diameter (p = 0.02) and a smaller cup/disc ratio (p < 0.001). The CRA emergence was largely within the nasal zone for both groups. The distinctive angioarchitecture of the optic disc in ODD patients can play a role in understanding the pathogenic cause of ODD.

AB - The aim was to analyse the optic disc angioarchitecture in optic disc drusen (ODD) patients using computer-based fundus analysis in a case–control study. Compared with controls the ODD group had a significantly more centralised central retinal artery (CRA) emergence (p < 0.001) and primary CRA branching (p = 0.008), a higher number of CRA bifurcations (p = 0.02), a larger vertical optic disc diameter (p = 0.02) and a smaller cup/disc ratio (p < 0.001). The CRA emergence was largely within the nasal zone for both groups. The distinctive angioarchitecture of the optic disc in ODD patients can play a role in understanding the pathogenic cause of ODD.

KW - Optic disc drusen

KW - optic nerve head angioarchitecture

KW - optic nerve head drusen

KW - optic nerve head microvasculature

UR - http://www.scopus.com/inward/record.url?scp=85079216160&partnerID=8YFLogxK

U2 - 10.1080/01658107.2019.1613666

DO - 10.1080/01658107.2019.1613666

M3 - Journal article

VL - 44

SP - 5

EP - 10

JO - Neuro-Ophthalmology

JF - Neuro-Ophthalmology

SN - 0077-7803

IS - 1

ER -

ID: 59339111