The added value of Bayesian interim analysis in randomized phase II and phase III clinical trials in hemato-oncology

Anna J T Smit; Niek G Van der Maas; Bronno Van der Holt; Yvette Van Norden; Erik Van Werkhoven; Annette Juul Vangsted; Paula F Ypma; Heleen A Visser-Wisselaar; Rossella Troia; Mario Boccadoro; Bob Löwenberg; Jeroen J W M Janssen; Gert J Ossenkoppele; Fredrik Schjesvold; Pieter Sonneveld; Sonja Zweegman; Jurjen Versluis; Jan J Cornelissen

doi:10.3324/haematol.2025.288675

The added value of Bayesian interim analysis in randomized phase II and phase III clinical trials in hemato-oncology

Anna J T Smit, Niek G Van der Maas, Bronno Van der Holt, Yvette Van Norden, Erik Van Werkhoven, Annette Juul Vangsted, Paula F Ypma, Heleen A Visser-Wisselaar, Rossella Troia, Mario Boccadoro, Bob Löwenberg, Jeroen J W M Janssen, Gert J Ossenkoppele, Fredrik Schjesvold, Pieter Sonneveld, Sonja Zweegman, Jurjen Versluis, Jan J Cornelissen

Afdeling for Blodsygdomme CKO

Abstract

Not available.

Originalsprog	Engelsk
Tidsskrift	Haematologica
ISSN	0390-6078
DOI	https://doi.org/10.3324/haematol.2025.288675
Status	E-pub ahead of print - 2 okt. 2025

Adgang til dokumentet

10.3324/haematol.2025.288675

Citationsformater

Smit, A. J. T., Van der Maas, N. G., Van der Holt, B., Van Norden, Y., Van Werkhoven, E., Vangsted, A. J., Ypma, P. F., Visser-Wisselaar, H. A., Troia, R., Boccadoro, M., Löwenberg, B., Janssen, J. J. W. M., Ossenkoppele, G. J., Schjesvold, F., Sonneveld, P., Zweegman, S., Versluis, J., & Cornelissen, J. J. (2025). The added value of Bayesian interim analysis in randomized phase II and phase III clinical trials in hemato-oncology. Haematologica. Advance online publication. https://doi.org/10.3324/haematol.2025.288675

Smit, AJT, Van der Maas, NG, Van der Holt, B, Van Norden, Y, Van Werkhoven, E, Vangsted, AJ, Ypma, PF, Visser-Wisselaar, HA, Troia, R, Boccadoro, M, Löwenberg, B, Janssen, JJWM, Ossenkoppele, GJ, Schjesvold, F, Sonneveld, P, Zweegman, S, Versluis, J & Cornelissen, JJ 2025, 'The added value of Bayesian interim analysis in randomized phase II and phase III clinical trials in hemato-oncology', Haematologica. https://doi.org/10.3324/haematol.2025.288675

@article{db2439f417e34e0f9f386756c35a0095,

title = "The added value of Bayesian interim analysis in randomized phase II and phase III clinical trials in hemato-oncology",

abstract = "Not available.",

author = "Smit, {Anna J T} and {Van der Maas}, {Niek G} and {Van der Holt}, Bronno and {Van Norden}, Yvette and {Van Werkhoven}, Erik and Vangsted, {Annette Juul} and Ypma, {Paula F} and Visser-Wisselaar, {Heleen A} and Rossella Troia and Mario Boccadoro and Bob L{\"o}wenberg and Janssen, {Jeroen J W M} and Ossenkoppele, {Gert J} and Fredrik Schjesvold and Pieter Sonneveld and Sonja Zweegman and Jurjen Versluis and Cornelissen, {Jan J}",

year = "2025",

month = oct,

day = "2",

doi = "10.3324/haematol.2025.288675",

language = "English",

journal = "Haematologica",

issn = "0390-6078",

publisher = "Ferrata Storti Foundation",

}

TY - JOUR

T1 - The added value of Bayesian interim analysis in randomized phase II and phase III clinical trials in hemato-oncology

AU - Smit, Anna J T

AU - Van der Maas, Niek G

AU - Van der Holt, Bronno

AU - Van Norden, Yvette

AU - Van Werkhoven, Erik

AU - Vangsted, Annette Juul

AU - Ypma, Paula F

AU - Visser-Wisselaar, Heleen A

AU - Troia, Rossella

AU - Boccadoro, Mario

AU - Löwenberg, Bob

AU - Janssen, Jeroen J W M

AU - Ossenkoppele, Gert J

AU - Schjesvold, Fredrik

AU - Sonneveld, Pieter

AU - Zweegman, Sonja

AU - Versluis, Jurjen

AU - Cornelissen, Jan J

PY - 2025/10/2

Y1 - 2025/10/2

N2 - Not available.

AB - Not available.

U2 - 10.3324/haematol.2025.288675

DO - 10.3324/haematol.2025.288675

M3 - Letter

C2 - 41035401

SN - 0390-6078

JO - Haematologica

JF - Haematologica

ER -

The added value of Bayesian interim analysis in randomized phase II and phase III clinical trials in hemato-oncology

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater