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The accuracy of titanium contrast-enhanced mammography: a retrospective multicentric study

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Harvard

González-Huebra, I, Malmierca, P, Elizalde, A, Etxano, J, Vejborg, I, Uhlenbrock, D & Pina, L 2020, 'The accuracy of titanium contrast-enhanced mammography: a retrospective multicentric study', Acta Radiologica, bind 61, nr. 10, s. 1335-1342. https://doi.org/10.1177/0284185119900440

APA

González-Huebra, I., Malmierca, P., Elizalde, A., Etxano, J., Vejborg, I., Uhlenbrock, D., & Pina, L. (2020). The accuracy of titanium contrast-enhanced mammography: a retrospective multicentric study. Acta Radiologica, 61(10), 1335-1342. https://doi.org/10.1177/0284185119900440

CBE

González-Huebra I, Malmierca P, Elizalde A, Etxano J, Vejborg I, Uhlenbrock D, Pina L. 2020. The accuracy of titanium contrast-enhanced mammography: a retrospective multicentric study. Acta Radiologica. 61(10):1335-1342. https://doi.org/10.1177/0284185119900440

MLA

Vancouver

González-Huebra I, Malmierca P, Elizalde A, Etxano J, Vejborg I, Uhlenbrock D o.a. The accuracy of titanium contrast-enhanced mammography: a retrospective multicentric study. Acta Radiologica. 2020 okt.;61(10):1335-1342. https://doi.org/10.1177/0284185119900440

Author

González-Huebra, Ignacio ; Malmierca, Patricia ; Elizalde, Arlette ; Etxano, Jon ; Vejborg, Ilse ; Uhlenbrock, Detlev ; Pina, Luis. / The accuracy of titanium contrast-enhanced mammography : a retrospective multicentric study. I: Acta Radiologica. 2020 ; Bind 61, Nr. 10. s. 1335-1342.

Bibtex

@article{711c3ddf3397423fb461107bf5d2ffd6,
title = "The accuracy of titanium contrast-enhanced mammography: a retrospective multicentric study",
abstract = "BACKGROUND: Recently, a new mammography system to perform contrast-enhanced mammography has become available in the market. For the high-energy acquisition, it uses a titanium filter instead of a copper one, reducing the tube load while maintaining image quality.PURPOSE: To retrospectively evaluate the accuracy of contrast-enhanced mammography with a titanium filter (TiCEM) in three readers with different grades of experience.MATERIAL AND METHODS: IRB-approved retrospective multicentric lesion by lesion study with 200 lesions, all of them initially classified as BI-RADS categories 0/3/4/5 on mammography and/or ultrasound and with pathological confirmation, in 135 patients. Three readers with different levels of experience (expert, resident, intermediate) blinded to the final diagnosis, retrospectively evaluated the low-energy (LE) images and the combination of LE and recombined (subtracted) images and classified the lesions according to the BI-RADS categories. Reader 1 also categorized the breast density. ROC curves were performed for each reader.RESULTS: Out of the 200 lesions, 82 were benign and 118 malignant (20 DCIS, 10 ILC, 88 IDC). The AUCs of LE versus TiCEM for were: Reader 1: 0.7 vs. 0.88, P < 0.001; Reader 2: 0.63 vs. 0.83, P < 0.001; and Reader 3: 0.63 vs. 0.84, P < 0.001. For the three readers, the AUCs of LE versus TiCEM were significantly superior in both dense and non-dense breasts (P < 0.001). Comparing the AUC of LE for Reader 1 (expert) versus the AUC of TiCEM for Reader 2 (resident) there were significant differences (0.7 vs. 0.83, P < 0.001).CONCLUSION: The accuracy of TiCEM was significantly better for all the readers, in both dense and non-dense breasts. The accuracy of a resident reading a TiCEM study was better than the accuracy of an expert radiologist reading LE images.",
keywords = "Aged, Breast Neoplasms/diagnostic imaging, Contrast Media, Female, Humans, Mammography/instrumentation, Middle Aged, Retrospective Studies, Sensitivity and Specificity, Titanium/chemistry",
author = "Ignacio Gonz{\'a}lez-Huebra and Patricia Malmierca and Arlette Elizalde and Jon Etxano and Ilse Vejborg and Detlev Uhlenbrock and Luis Pina",
year = "2020",
month = oct,
doi = "10.1177/0284185119900440",
language = "English",
volume = "61",
pages = "1335--1342",
journal = "Acta Radiologica",
issn = "0284-1851",
publisher = "Informa Healthcare",
number = "10",

}

RIS

TY - JOUR

T1 - The accuracy of titanium contrast-enhanced mammography

T2 - a retrospective multicentric study

AU - González-Huebra, Ignacio

AU - Malmierca, Patricia

AU - Elizalde, Arlette

AU - Etxano, Jon

AU - Vejborg, Ilse

AU - Uhlenbrock, Detlev

AU - Pina, Luis

PY - 2020/10

Y1 - 2020/10

N2 - BACKGROUND: Recently, a new mammography system to perform contrast-enhanced mammography has become available in the market. For the high-energy acquisition, it uses a titanium filter instead of a copper one, reducing the tube load while maintaining image quality.PURPOSE: To retrospectively evaluate the accuracy of contrast-enhanced mammography with a titanium filter (TiCEM) in three readers with different grades of experience.MATERIAL AND METHODS: IRB-approved retrospective multicentric lesion by lesion study with 200 lesions, all of them initially classified as BI-RADS categories 0/3/4/5 on mammography and/or ultrasound and with pathological confirmation, in 135 patients. Three readers with different levels of experience (expert, resident, intermediate) blinded to the final diagnosis, retrospectively evaluated the low-energy (LE) images and the combination of LE and recombined (subtracted) images and classified the lesions according to the BI-RADS categories. Reader 1 also categorized the breast density. ROC curves were performed for each reader.RESULTS: Out of the 200 lesions, 82 were benign and 118 malignant (20 DCIS, 10 ILC, 88 IDC). The AUCs of LE versus TiCEM for were: Reader 1: 0.7 vs. 0.88, P < 0.001; Reader 2: 0.63 vs. 0.83, P < 0.001; and Reader 3: 0.63 vs. 0.84, P < 0.001. For the three readers, the AUCs of LE versus TiCEM were significantly superior in both dense and non-dense breasts (P < 0.001). Comparing the AUC of LE for Reader 1 (expert) versus the AUC of TiCEM for Reader 2 (resident) there were significant differences (0.7 vs. 0.83, P < 0.001).CONCLUSION: The accuracy of TiCEM was significantly better for all the readers, in both dense and non-dense breasts. The accuracy of a resident reading a TiCEM study was better than the accuracy of an expert radiologist reading LE images.

AB - BACKGROUND: Recently, a new mammography system to perform contrast-enhanced mammography has become available in the market. For the high-energy acquisition, it uses a titanium filter instead of a copper one, reducing the tube load while maintaining image quality.PURPOSE: To retrospectively evaluate the accuracy of contrast-enhanced mammography with a titanium filter (TiCEM) in three readers with different grades of experience.MATERIAL AND METHODS: IRB-approved retrospective multicentric lesion by lesion study with 200 lesions, all of them initially classified as BI-RADS categories 0/3/4/5 on mammography and/or ultrasound and with pathological confirmation, in 135 patients. Three readers with different levels of experience (expert, resident, intermediate) blinded to the final diagnosis, retrospectively evaluated the low-energy (LE) images and the combination of LE and recombined (subtracted) images and classified the lesions according to the BI-RADS categories. Reader 1 also categorized the breast density. ROC curves were performed for each reader.RESULTS: Out of the 200 lesions, 82 were benign and 118 malignant (20 DCIS, 10 ILC, 88 IDC). The AUCs of LE versus TiCEM for were: Reader 1: 0.7 vs. 0.88, P < 0.001; Reader 2: 0.63 vs. 0.83, P < 0.001; and Reader 3: 0.63 vs. 0.84, P < 0.001. For the three readers, the AUCs of LE versus TiCEM were significantly superior in both dense and non-dense breasts (P < 0.001). Comparing the AUC of LE for Reader 1 (expert) versus the AUC of TiCEM for Reader 2 (resident) there were significant differences (0.7 vs. 0.83, P < 0.001).CONCLUSION: The accuracy of TiCEM was significantly better for all the readers, in both dense and non-dense breasts. The accuracy of a resident reading a TiCEM study was better than the accuracy of an expert radiologist reading LE images.

KW - Aged

KW - Breast Neoplasms/diagnostic imaging

KW - Contrast Media

KW - Female

KW - Humans

KW - Mammography/instrumentation

KW - Middle Aged

KW - Retrospective Studies

KW - Sensitivity and Specificity

KW - Titanium/chemistry

U2 - 10.1177/0284185119900440

DO - 10.1177/0284185119900440

M3 - Journal article

C2 - 31979977

VL - 61

SP - 1335

EP - 1342

JO - Acta Radiologica

JF - Acta Radiologica

SN - 0284-1851

IS - 10

ER -

ID: 61864731