The 2013 International Society for Heart and Lung Transplantation Working Formulation for the standardization of nomenclature in the pathologic diagnosis of antibody-mediated rejection in heart transplantation

Gerald J Berry, Margaret M Burke, Claus Andersen, Patrick Bruneval, Marny Fedrigo, Michael C Fishbein, Martin Goddard, Elizabeth H Hammond, Ornella Leone, Charles Marboe, Dylan Miller, Desley Neil, Doris Rassl, Monica P Revelo, Alexandra Rice, E Rene Rodriguez, Susan Stewart, Carmela D Tan, Gayle L Winters, Lori WestMandeep R Mehra, Annalisa Angelini

440 Citationer (Scopus)

Abstract

During the last 25 years, antibody-mediated rejection of the cardiac allograft has evolved from a relatively obscure concept to a recognized clinical complication in the management of heart transplant patients. Herein we report the consensus findings from a series of meetings held between 2010-2012 to develop a Working Formulation for the pathologic diagnosis, grading, and reporting of cardiac antibody-mediated rejection. The diagnostic criteria for its morphologic and immunopathologic components are enumerated, illustrated, and described in detail. Numerous challenges and unresolved clinical, immunologic, and pathologic questions remain to which a Working Formulation may facilitate answers.
OriginalsprogEngelsk
TidsskriftThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Vol/bind32
Udgave nummer12
Sider (fra-til)1147-62
Antal sider16
ISSN1053-2498
DOI
StatusUdgivet - dec. 2013

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