Abstract
During the last 25 years, antibody-mediated rejection of the cardiac allograft has evolved from a relatively obscure concept to a recognized clinical complication in the management of heart transplant patients. Herein we report the consensus findings from a series of meetings held between 2010-2012 to develop a Working Formulation for the pathologic diagnosis, grading, and reporting of cardiac antibody-mediated rejection. The diagnostic criteria for its morphologic and immunopathologic components are enumerated, illustrated, and described in detail. Numerous challenges and unresolved clinical, immunologic, and pathologic questions remain to which a Working Formulation may facilitate answers.
Originalsprog | Engelsk |
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Tidsskrift | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation |
Vol/bind | 32 |
Udgave nummer | 12 |
Sider (fra-til) | 1147-62 |
Antal sider | 16 |
ISSN | 1053-2498 |
DOI | |
Status | Udgivet - dec. 2013 |