@article{2e38ec73e3be4029a67d9d035b9b8079,
title = "Tests for genetic interactions in type 1 diabetes: linkage and stratification analyses of 4,422 affected sib-pairs",
abstract = "Interactions between genetic and environmental factors lead to immune dysregulation causing type 1 diabetes and other autoimmune disorders. Recently, many common genetic variants have been associated with type 1 diabetes risk, but each has modest individual effects. Familial clustering of type 1 diabetes has not been explained fully and could arise from many factors, including undetected genetic variation and gene interactions.",
keywords = "Analysis of Variance, Chromosome Mapping, Diabetes Mellitus, Type 1, Female, Genetic Linkage, Genetic Loci, Genetic Predisposition to Disease, Genotype, Humans, Male, Risk Factors, Siblings",
author = "Grant Morahan and Munish Mehta and Ian James and Wei-Min Chen and Beena Akolkar and Erlich, {Henry A} and Hilner, {Joan E} and C{\'e}cile Julier and J{\o}rn Nerup and Concepcion Nierras and Flemming Pociot and Todd, {John A} and Rich, {Stephen S} and {Type 1 Diabetes Genetics Consortium}",
year = "2011",
month = mar,
doi = "10.2337/db10-1195",
language = "English",
volume = "60",
pages = "1030--40",
journal = "Diabetes",
issn = "0012-1797",
publisher = "American Diabetes Association",
number = "3",
}