Temporal trends in utilization of transcatheter aortic valve replacement and patient characteristics: a nationwide study

Jarl E Strange*, Caroline Sindet-Pedersen, Gunnar H Gislason, Christian Torp-Pedersen, Kristian H Kragholm, Camilla Lundahl, Emil L Fosbøl, Jawad H Butt, Lars Køber, Lars Søndergaard, Jonas B Olesen

*Corresponding author af dette arbejde

Abstract

AIM: To investigate trends in the utilization of transcatheter aortic valve replacement (TAVR) and changes in the characteristics of patients undergoing first-time TAVR.

METHODS: Using Danish nationwide registers, we included all patients undergoing TAVR between 2008 and 2020. To compare patient characteristics, the study population was stratified according to calendar year of procedure: 2008-2010, 2011-2013, 2014-2016, and 2017-2020.

RESULTS: We identified 6,097 patients undergoing TAVR with year-by-year increases in TAVR penetration rate. Over time, the age of the patients remained stable (2008-2010: median age 82 year [interquartile range (IQR): 77-86] vs 2017-2020: median age 81 years [IQR: 77-85]). Moreover, there was an increase in male patients (2008-2010: 49.9% vs 2017-2020: 57.4%) and patients with diabetes (2008-2010: 14.2% vs 2017-2020: 19.2%). Conversely, a history of stroke (2008-2010: 15.8% vs 2017-2020: 13.1%), previous myocardial infarction (2008-2010: 22.4% vs 2017-2020: 10.0%), heart failure (2008-2010: 40.5% vs 2017-2020: 25.2%), and peripheral artery disease (2008-2010: 14.8% vs 2017-2020: 10.4) decreased among patients.

CONCLUSIONS: TAVR utilization increased markedly in the years 2008-2020. Patients undergoing TAVR had less comorbidity over time while age remained stable. Thus, despite expanding to patients at lower surgical risk, TAVR is still offered mainly to older patients.

OriginalsprogEngelsk
TidsskriftAmerican Heart Journal
Vol/bind243
Sider (fra-til)140-146
Antal sider7
ISSN0002-8703
DOI
StatusUdgivet - 2022

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