Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure

Palle B Jeppesen, Marek Pertkiewicz, Bernard Messing, Kishore Iyer, Douglas L Seidner, Stephen J D O'keefe, Alastair Forbes, Hartmut Heinze, Bo Joelsson

    389 Citationer (Scopus)

    Abstract

    Teduglutide, a glucagon-like peptide 2 analogue, might restore intestinal structural and functional integrity by promoting growth of the mucosa and reducing gastric emptying and secretion. These factors could increase fluid and nutrient absorption in patients with short bowel syndrome with intestinal failure (SBS-IF). We performed a prospective study to determine whether teduglutide reduces parenteral support in patients with SBS-IF.
    OriginalsprogEngelsk
    TidsskriftGastroenterology
    Vol/bind143
    Udgave nummer6
    Sider (fra-til)1473-1481.e3
    Antal sider9
    ISSN0016-5085
    DOI
    StatusUdgivet - 2012

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