TY - JOUR
T1 - TAVR for All?
T2 - The Surgical Perspective
AU - Zhang, Xiling
AU - Puehler, Thomas
AU - Frank, Derk
AU - Sathananthan, Janarthanan
AU - Sellers, Stephanie
AU - Meier, David
AU - Both, Marcus
AU - Blanke, Philipp
AU - Seoudy, Hatim
AU - Saad, Mohammed
AU - Müller, Oliver J
AU - Sondergaard, Lars
AU - Lutter, Georg
PY - 2022/7/12
Y1 - 2022/7/12
N2 - In spite of the noninferiority of transcatheter aortic valve replacement (TAVR) in high- and intermediate-risk patients, there are still obstacles that need to be overcome before the procedure is further expanded and clinically integrated. The lack of evidence on the long-term durability of the bioprostheses used for TAVR remains of particular concern. In addition, surgery may be preferred over TAVR in patients with bicuspid aortic valve (BAV) or with concomitant pathologies such as other valve diseases (mitral regurgitation/tricuspid regurgitation), aortopathy, and coronary artery disease. In this review, we discuss and summarize relevant data from clinical trials, current trends, and remaining obstacles, and provide our perspective on the indications for the expansion of TAVR.
AB - In spite of the noninferiority of transcatheter aortic valve replacement (TAVR) in high- and intermediate-risk patients, there are still obstacles that need to be overcome before the procedure is further expanded and clinically integrated. The lack of evidence on the long-term durability of the bioprostheses used for TAVR remains of particular concern. In addition, surgery may be preferred over TAVR in patients with bicuspid aortic valve (BAV) or with concomitant pathologies such as other valve diseases (mitral regurgitation/tricuspid regurgitation), aortopathy, and coronary artery disease. In this review, we discuss and summarize relevant data from clinical trials, current trends, and remaining obstacles, and provide our perspective on the indications for the expansion of TAVR.
UR - http://www.scopus.com/inward/record.url?scp=85135558264&partnerID=8YFLogxK
U2 - 10.3390/jcdd9070223
DO - 10.3390/jcdd9070223
M3 - Review
C2 - 35877585
SN - 2308-3425
VL - 9
JO - Journal of cardiovascular development and disease
JF - Journal of cardiovascular development and disease
IS - 7
M1 - 223
ER -