Targeting BKCa Channels in Migraine: Rationale and Perspectives

Keyphrases

• Migraine 100%
• BK Channel 100%
• Migraine Patients 25%
• Channel Openers 25%
• Glyceryl Trinitrate 12%
• Headache 12%
• Healthy Volunteers 12%
• Neuronal Excitability 12%
• Adverse Effects 12%
• Placebo-controlled 12%
• Calcitonin Gene-related Peptide 12%
• Antimigraine Drugs 12%
• Migraine Pathophysiology 12%
• Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) 12%
• High Affinity 12%
• Trigeminal Ganglion 12%
• Calcium-activated Potassium 12%
• Trigeminal System 12%
• Channel Blocker 12%
• Conductance 12%
• Signaling Pathway 12%
• Vascular Tonus 12%
• Channel Activation 12%
• Mitochondrial Potassium Channels 12%
• Close-coupling 12%
• Downstream Molecules 12%
• Cranial Arteries 12%
• Controlled Clinical Study 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Migraine 100%
• Large Conductance Calcium Activated Potassium Channel 100%
• Channel Opener 22%
• Pathophysiology 11%
• Headache 11%
• Glyceryl Trinitrate 11%
• Placebo 11%
• Calcitonin Gene Related Peptide 11%
• Normal Human 11%
• Isotopes of Potassium 11%
• Adenosine Triphosphate 11%
• Clinical Study 11%
• Adenosine Triphosphate Sensitive Potassium Channel 11%
• Hypophysis Adenylate Cyclase Activating Polypeptide 11%
• Potassium 11%
• Adverse Effect 11%