Systemic steroid reduces long-term hearing loss in experimental pneumococcal meningitis

Lise Lotte Worsøe; C.T. Brandt; S.P. Lund; Christian Østergaard Andersen; J. Thomsen; P. Caye-Thomasen

doi:10.1002/lary.21007

Systemic steroid reduces long-term hearing loss in experimental pneumococcal meningitis

Lise Lotte Worsøe, C.T. Brandt, S.P. Lund, Christian Østergaard Andersen, J. Thomsen, P. Caye-Thomasen

10 Citationer (Scopus)

Abstract

Sensorineural hearing loss is a common complication of pneumococcal meningitis. Treatment with corticosteroids reduces inflammatory response and may thereby reduce hearing loss. However, both experimental studies and clinical trials investigating the effect of corticosteroids on hearing loss have generated conflicting results. The objective of the present study was to determine whether systemic steroid treatment had an effect on hearing loss and cochlear damage in a rat model of pneumococcal meningitis.

Originalsprog	Engelsk
Tidsskrift	The Laryngoscope
Vol/bind	120
Udgave nummer	9
Sider (fra-til)	1872-9
Antal sider	8
DOI	https://doi.org/10.1002/lary.21007
Status	Udgivet - 2010

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10.1002/lary.21007

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title = "Systemic steroid reduces long-term hearing loss in experimental pneumococcal meningitis",

abstract = "Sensorineural hearing loss is a common complication of pneumococcal meningitis. Treatment with corticosteroids reduces inflammatory response and may thereby reduce hearing loss. However, both experimental studies and clinical trials investigating the effect of corticosteroids on hearing loss have generated conflicting results. The objective of the present study was to determine whether systemic steroid treatment had an effect on hearing loss and cochlear damage in a rat model of pneumococcal meningitis.",

author = "Wors{\o}e, \{Lise Lotte\} and C.T. Brandt and S.P. Lund and Andersen, \{Christian {\O}stergaard\} and J. Thomsen and P. Caye-Thomasen",

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language = "English",

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TY - JOUR

T1 - Systemic steroid reduces long-term hearing loss in experimental pneumococcal meningitis

AU - Worsøe, Lise Lotte

AU - Brandt, C.T.

AU - Lund, S.P.

AU - Andersen, Christian Østergaard

AU - Thomsen, J.

AU - Caye-Thomasen, P.

PY - 2010

Y1 - 2010

N2 - Sensorineural hearing loss is a common complication of pneumococcal meningitis. Treatment with corticosteroids reduces inflammatory response and may thereby reduce hearing loss. However, both experimental studies and clinical trials investigating the effect of corticosteroids on hearing loss have generated conflicting results. The objective of the present study was to determine whether systemic steroid treatment had an effect on hearing loss and cochlear damage in a rat model of pneumococcal meningitis.

AB - Sensorineural hearing loss is a common complication of pneumococcal meningitis. Treatment with corticosteroids reduces inflammatory response and may thereby reduce hearing loss. However, both experimental studies and clinical trials investigating the effect of corticosteroids on hearing loss have generated conflicting results. The objective of the present study was to determine whether systemic steroid treatment had an effect on hearing loss and cochlear damage in a rat model of pneumococcal meningitis.

UR - https://www.scopus.com/pages/publications/77956575935

U2 - 10.1002/lary.21007

DO - 10.1002/lary.21007

M3 - Journal article

C2 - 20717948

SN - 1091-756X

VL - 120

SP - 1872

EP - 1879

JO - The Laryngoscope

JF - The Laryngoscope

IS - 9

ER -

Systemic steroid reduces long-term hearing loss in experimental pneumococcal meningitis

Abstract

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