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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Systematic Assessment of Difficult-to-Treat Asthma: Principles and Perspectives

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

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  • Mark Hew
  • Andrew Menzies-Gow
  • James H Hull
  • Louise Fleming
  • Celeste Porsbjerg
  • Anneke Ten Brinke
  • David Allen
  • Robin Gore
  • Tunn Ren Tay
Vis graf over relationer

Difficult-to-treat asthma affects a minority of adults and children with asthma but represents a challenging mix of misdiagnosis, multimorbidity, inadequate self-management, severe airway pathobiology, and treatment complications. Management of these patients extends beyond asthma pharmacotherapy, because multiple other patient-related domains need to be addressed as well. Such complexity can hinder adequate clinical assessment even when performed in specialist practice. Systematic assessment undertaken by specialized multidisciplinary teams brings a broad range of resources to bear on patients with difficult-to-treat asthma. Although the concept of systematic assessment is not new, practices vary considerably and implementation is not universal. Nevertheless, assessment protocols are already in place in several institutions worldwide, and outcomes after such assessments have been highly encouraging. This review discusses the rationale, components, and benefits of systematic assessment, outlining its clinical utility and the available evidence for improved outcomes. It describes a range of service configurations and assessment approaches, drawing examples from severe asthma centers around the world to highlight common essential elements. It also provides a framework for establishing such services and discusses practical considerations for implementation.

OriginalsprogEngelsk
TidsskriftThe journal of allergy and clinical immunology. In practice
Vol/bind8
Udgave nummer7
Sider (fra-til)2222-2233
Antal sider12
ISSN2213-2198
DOI
StatusUdgivet - 8 aug. 2020

Bibliografisk note

Copyright © 2020 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

ID: 60518442