Svær føtal anæmi på grund af uerkendt alloimmunisering hos RhD-positiv gravid kvinde

Rikke Krabek; Thomas Bergholt; Marianne Johansen; Lone Nikoline Nørgaard; Christian Heiring; Morten Hanefeld Dziegiel; Charlotte Kvist Ekelund

Svær føtal anæmi på grund af uerkendt alloimmunisering hos RhD-positiv gravid kvinde

Rikke Krabek, Thomas Bergholt, Marianne Johansen, Lone Nikoline Nørgaard, Christian Heiring, Morten Hanefeld Dziegiel, Charlotte Kvist Ekelund

Abstract

The incidence of haemolytic disease of the foetus or newborn (HDFN) has decreased considerably in Denmark since the introduction of routine administration of prophylactic anti-D immunoglobulin to RhD-negative pregnant women carrying a RhD-positive foetus. RhD-positive pregnant women are screened for irregular antibodies only in the first trimester of their pregnancy, as their risk of clinically relevant immunisation during pregnancy has been considered very low. This is a case report of severe undetected alloimmunisation causing fatal HDFN after the first trimester in a RhD-positive woman.

Bidragets oversatte titel	Severe foetal anaemia caused by undetected alloimmunisation in a RhD-positive pregnant woman
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	183
Udgave nummer	32
Sider (fra-til)	V02210124
ISSN	0041-5782
Status	Udgivet - 9 aug. 2021

Emneord

Anemia, Hemolytic, Autoimmune
Erythroblastosis, Fetal/etiology
Female
Fetus
Humans
Infant, Newborn
Isoantibodies
Pregnancy
Pregnant Women

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https://ugeskriftet.dk/videnskab/svaer-fotal-anaemi-pa-grund-af-uerkendt-alloimmunisering-hos-rhd-positiv-gravid-kvinde

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Citationsformater

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abstract = "The incidence of haemolytic disease of the foetus or newborn (HDFN) has decreased considerably in Denmark since the introduction of routine administration of prophylactic anti-D immunoglobulin to RhD-negative pregnant women carrying a RhD-positive foetus. RhD-positive pregnant women are screened for irregular antibodies only in the first trimester of their pregnancy, as their risk of clinically relevant immunisation during pregnancy has been considered very low. This is a case report of severe undetected alloimmunisation causing fatal HDFN after the first trimester in a RhD-positive woman.",

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T1 - Svær føtal anæmi på grund af uerkendt alloimmunisering hos RhD-positiv gravid kvinde

AU - Krabek, Rikke

AU - Bergholt, Thomas

AU - Johansen, Marianne

AU - Nørgaard, Lone Nikoline

AU - Heiring, Christian

AU - Dziegiel, Morten Hanefeld

AU - Ekelund, Charlotte Kvist

PY - 2021/8/9

Y1 - 2021/8/9

N2 - The incidence of haemolytic disease of the foetus or newborn (HDFN) has decreased considerably in Denmark since the introduction of routine administration of prophylactic anti-D immunoglobulin to RhD-negative pregnant women carrying a RhD-positive foetus. RhD-positive pregnant women are screened for irregular antibodies only in the first trimester of their pregnancy, as their risk of clinically relevant immunisation during pregnancy has been considered very low. This is a case report of severe undetected alloimmunisation causing fatal HDFN after the first trimester in a RhD-positive woman.

AB - The incidence of haemolytic disease of the foetus or newborn (HDFN) has decreased considerably in Denmark since the introduction of routine administration of prophylactic anti-D immunoglobulin to RhD-negative pregnant women carrying a RhD-positive foetus. RhD-positive pregnant women are screened for irregular antibodies only in the first trimester of their pregnancy, as their risk of clinically relevant immunisation during pregnancy has been considered very low. This is a case report of severe undetected alloimmunisation causing fatal HDFN after the first trimester in a RhD-positive woman.

KW - Anemia, Hemolytic, Autoimmune

KW - Erythroblastosis, Fetal/etiology

KW - Female

KW - Fetus

KW - Humans

KW - Infant, Newborn

KW - Isoantibodies

KW - Pregnancy

KW - Pregnant Women

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M3 - Tidsskriftartikel

C2 - 34378528

SN - 0041-5782

VL - 183

SP - V02210124

JO - Ugeskrift for Laeger

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ER -

Svær føtal anæmi på grund af uerkendt alloimmunisering hos RhD-positiv gravid kvinde

Abstract

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