Surgical treatment of breast cancer

Tove Filtenborg Tvedskov; Marianne Djernes Lautrup; Niels Thorndal Kroman; Peer Michael Christiansen

doi:10.61409/V01230033

Surgical treatment of breast cancer

Tove Filtenborg Tvedskov, Marianne Djernes Lautrup, Niels Thorndal Kroman, Peer Michael Christiansen

Brystkirurgi

Abstract

Surgical treatment of breast cancer has changed towards less invasive procedures as summarised in this review. Breast conserving surgery (BCS) and radiotherapy (RT) are now recommended as standard of care. Several flexible marking methods for removal of non-palpable tumours have gradually replaced wire-guided localisation. Neoadjuvant systemic treatment increases tumour shrinkage and BCS and may lead to omission of axillary clearance (AC). The prognostic significance of AC in patients with metastases to 1-2 sentinel nodes at primary surgery is questioned. Results from the SENOMAC trial are expected to change guidelines from AC to axillary RT.

Bidragets oversatte titel	Not Available
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	186
Udgave nummer	12
ISSN	0041-5782
DOI	https://doi.org/10.61409/V01230033
Status	Udgivet - 18 mar. 2024

Emneord

Humans
Female
Breast Neoplasms/pathology
Lymphatic Metastasis
Sentinel Lymph Node Biopsy
Lymph Node Excision
Mastectomy, Segmental
Axilla/pathology
Lymph Nodes/pathology

Adgang til dokumentet

10.61409/V01230033

Andre filer og links

Link to publication in Scopus

Citationsformater

@article{085a7b1812f94d2fa1248caa4d0435e8,

title = "Surgical treatment of breast cancer",

abstract = "Surgical treatment of breast cancer has changed towards less invasive procedures as summarised in this review. Breast conserving surgery (BCS) and radiotherapy (RT) are now recommended as standard of care. Several flexible marking methods for removal of non-palpable tumours have gradually replaced wire-guided localisation. Neoadjuvant systemic treatment increases tumour shrinkage and BCS and may lead to omission of axillary clearance (AC). The prognostic significance of AC in patients with metastases to 1-2 sentinel nodes at primary surgery is questioned. Results from the SENOMAC trial are expected to change guidelines from AC to axillary RT.",

keywords = "Humans, Female, Breast Neoplasms/pathology, Lymphatic Metastasis, Sentinel Lymph Node Biopsy, Lymph Node Excision, Mastectomy, Segmental, Axilla/pathology, Lymph Nodes/pathology",

author = "Tvedskov, {Tove Filtenborg} and Lautrup, {Marianne Djernes} and Kroman, {Niels Thorndal} and Christiansen, {Peer Michael}",

note = "Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.",

year = "2024",

month = mar,

day = "18",

doi = "10.61409/V01230033",

language = "Dansk",

volume = "186",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "12",

}

TY - JOUR

T1 - Surgical treatment of breast cancer

AU - Tvedskov, Tove Filtenborg

AU - Lautrup, Marianne Djernes

AU - Kroman, Niels Thorndal

AU - Christiansen, Peer Michael

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2024/3/18

Y1 - 2024/3/18

N2 - Surgical treatment of breast cancer has changed towards less invasive procedures as summarised in this review. Breast conserving surgery (BCS) and radiotherapy (RT) are now recommended as standard of care. Several flexible marking methods for removal of non-palpable tumours have gradually replaced wire-guided localisation. Neoadjuvant systemic treatment increases tumour shrinkage and BCS and may lead to omission of axillary clearance (AC). The prognostic significance of AC in patients with metastases to 1-2 sentinel nodes at primary surgery is questioned. Results from the SENOMAC trial are expected to change guidelines from AC to axillary RT.

AB - Surgical treatment of breast cancer has changed towards less invasive procedures as summarised in this review. Breast conserving surgery (BCS) and radiotherapy (RT) are now recommended as standard of care. Several flexible marking methods for removal of non-palpable tumours have gradually replaced wire-guided localisation. Neoadjuvant systemic treatment increases tumour shrinkage and BCS and may lead to omission of axillary clearance (AC). The prognostic significance of AC in patients with metastases to 1-2 sentinel nodes at primary surgery is questioned. Results from the SENOMAC trial are expected to change guidelines from AC to axillary RT.

KW - Humans

KW - Female

KW - Breast Neoplasms/pathology

KW - Lymphatic Metastasis

KW - Sentinel Lymph Node Biopsy

KW - Lymph Node Excision

KW - Mastectomy, Segmental

KW - Axilla/pathology

KW - Lymph Nodes/pathology

UR - http://www.scopus.com/inward/record.url?scp=85189128903&partnerID=8YFLogxK

U2 - 10.61409/V01230033

DO - 10.61409/V01230033

M3 - Review

C2 - 38533870

SN - 0041-5782

VL - 186

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 12

ER -

Surgical treatment of breast cancer

Abstract

Emneord

Adgang til dokumentet

Andre filer og links

Fingeraftryk

Citationsformater