Surgical treatment of breast cancer

Tove Filtenborg Tvedskov, Marianne Djernes Lautrup, Niels Thorndal Kroman, Peer Michael Christiansen


Surgical treatment of breast cancer has changed towards less invasive procedures as summarised in this review. Breast conserving surgery (BCS) and radiotherapy (RT) are now recommended as standard of care. Several flexible marking methods for removal of non-palpable tumours have gradually replaced wire-guided localisation. Neoadjuvant systemic treatment increases tumour shrinkage and BCS and may lead to omission of axillary clearance (AC). The prognostic significance of AC in patients with metastases to 1-2 sentinel nodes at primary surgery is questioned. Results from the SENOMAC trial are expected to change guidelines from AC to axillary RT.

Bidragets oversatte titelNot Available
TidsskriftUgeskrift for Laeger
Udgave nummer12
StatusUdgivet - 18 mar. 2024


  • Humans
  • Female
  • Breast Neoplasms/pathology
  • Lymphatic Metastasis
  • Sentinel Lymph Node Biopsy
  • Lymph Node Excision
  • Mastectomy, Segmental
  • Axilla/pathology
  • Lymph Nodes/pathology


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