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suPAR: The unspecific marker for disease presence, severity and prognosis

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@article{b56e2fae113346558840b01721c1e886,
title = "suPAR: The unspecific marker for disease presence, severity and prognosis",
abstract = "Investigation of biomarkers that can promptly predict unfavourable outcome of critically illness is an emerging necessity taking into consideration the need for early intervention, the shortage of available beds in intensive care units and the considerable cost of hospitalisation. The most promising biomarker is soluble urokinase-type plasminogen activator receptor (suPAR). Three studies in large populations of critically ill patients and patients admitted to the emergency department have shown that concentrations >12ng/mL can safely predict unfavourable outcome. This review presents a thorough analysis of the data from these studies.",
author = "Jesper Eugen-Olsen and Giamarellos-Bourboulis, {Evangelos J}",
note = "Copyright {\textcopyright} 2015 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.",
year = "2015",
month = dec,
doi = "10.1016/j.ijantimicag.2015.10.011",
language = "English",
volume = "41",
pages = "s33--s34",
journal = "International Journal of Antimicrobial Agents",
issn = "0924-8579",
publisher = "Elsevier BV",
number = "1",

}

RIS

TY - JOUR

T1 - suPAR

T2 - The unspecific marker for disease presence, severity and prognosis

AU - Eugen-Olsen, Jesper

AU - Giamarellos-Bourboulis, Evangelos J

N1 - Copyright © 2015 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

PY - 2015/12

Y1 - 2015/12

N2 - Investigation of biomarkers that can promptly predict unfavourable outcome of critically illness is an emerging necessity taking into consideration the need for early intervention, the shortage of available beds in intensive care units and the considerable cost of hospitalisation. The most promising biomarker is soluble urokinase-type plasminogen activator receptor (suPAR). Three studies in large populations of critically ill patients and patients admitted to the emergency department have shown that concentrations >12ng/mL can safely predict unfavourable outcome. This review presents a thorough analysis of the data from these studies.

AB - Investigation of biomarkers that can promptly predict unfavourable outcome of critically illness is an emerging necessity taking into consideration the need for early intervention, the shortage of available beds in intensive care units and the considerable cost of hospitalisation. The most promising biomarker is soluble urokinase-type plasminogen activator receptor (suPAR). Three studies in large populations of critically ill patients and patients admitted to the emergency department have shown that concentrations >12ng/mL can safely predict unfavourable outcome. This review presents a thorough analysis of the data from these studies.

U2 - 10.1016/j.ijantimicag.2015.10.011

DO - 10.1016/j.ijantimicag.2015.10.011

M3 - Journal article

C2 - 26603640

VL - 41

SP - s33-s34

JO - International Journal of Antimicrobial Agents

JF - International Journal of Antimicrobial Agents

SN - 0924-8579

IS - 1

ER -

ID: 45835451