Sunscreens in human plasma and urine after repeated whole-body topical application

N R Janjua; B Kongshoj; A-M Andersson; H C Wulf

doi:10.1111/j.1468-3083.2007.02492.x

Sunscreens in human plasma and urine after repeated whole-body topical application

N R Janjua, B Kongshoj, A-M Andersson, H C Wulf

225 Citationer (Scopus)

Abstract

The three chemical ultraviolet absorbers benzophenone-3 (BP-3), octyl-methoxycinnamate (OMC) and 3-(4-methylbenzylidene) camphor (4-MBC) are commercially used in sunscreens worldwide. Apart from sun protection, they may possess endocrine-disrupting effects in animals and in vitro. For all three compounds, only sporadic measurements of percutaneous absorption and excretion after topical application in humans have been described.

Originalsprog	Engelsk
Tidsskrift	European Academy of Dermatology and Venereology. Journal
Vol/bind	22
Udgave nummer	4
Sider (fra-til)	456-61
Antal sider	6
ISSN	0926-9959
DOI	https://doi.org/10.1111/j.1468-3083.2007.02492.x
Status	Udgivet - apr. 2008

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10.1111/j.1468-3083.2007.02492.x

Citationsformater

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title = "Sunscreens in human plasma and urine after repeated whole-body topical application",

abstract = "The three chemical ultraviolet absorbers benzophenone-3 (BP-3), octyl-methoxycinnamate (OMC) and 3-(4-methylbenzylidene) camphor (4-MBC) are commercially used in sunscreens worldwide. Apart from sun protection, they may possess endocrine-disrupting effects in animals and in vitro. For all three compounds, only sporadic measurements of percutaneous absorption and excretion after topical application in humans have been described.",

keywords = "Administration, Topical, Adult, Aged, Aged, 80 and over, Benzophenones, Camphor, Chromatography, High Pressure Liquid, Cinnamates, Female, Humans, Male, Middle Aged, Postmenopause, Skin Absorption, Statistics, Nonparametric, Sunscreening Agents",

author = "Janjua, {N R} and B Kongshoj and A-M Andersson and Wulf, {H C}",

year = "2008",

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doi = "10.1111/j.1468-3083.2007.02492.x",

language = "English",

volume = "22",

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journal = "European Academy of Dermatology and Venereology. Journal",

issn = "0926-9959",

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TY - JOUR

T1 - Sunscreens in human plasma and urine after repeated whole-body topical application

AU - Janjua, N R

AU - Kongshoj, B

AU - Andersson, A-M

AU - Wulf, H C

PY - 2008/4

Y1 - 2008/4

N2 - The three chemical ultraviolet absorbers benzophenone-3 (BP-3), octyl-methoxycinnamate (OMC) and 3-(4-methylbenzylidene) camphor (4-MBC) are commercially used in sunscreens worldwide. Apart from sun protection, they may possess endocrine-disrupting effects in animals and in vitro. For all three compounds, only sporadic measurements of percutaneous absorption and excretion after topical application in humans have been described.

AB - The three chemical ultraviolet absorbers benzophenone-3 (BP-3), octyl-methoxycinnamate (OMC) and 3-(4-methylbenzylidene) camphor (4-MBC) are commercially used in sunscreens worldwide. Apart from sun protection, they may possess endocrine-disrupting effects in animals and in vitro. For all three compounds, only sporadic measurements of percutaneous absorption and excretion after topical application in humans have been described.

KW - Administration, Topical

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Benzophenones

KW - Camphor

KW - Chromatography, High Pressure Liquid

KW - Cinnamates

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Postmenopause

KW - Skin Absorption

KW - Statistics, Nonparametric

KW - Sunscreening Agents

U2 - 10.1111/j.1468-3083.2007.02492.x

DO - 10.1111/j.1468-3083.2007.02492.x

M3 - Journal article

C2 - 18221342

SN - 0926-9959

VL - 22

SP - 456

EP - 461

JO - European Academy of Dermatology and Venereology. Journal

JF - European Academy of Dermatology and Venereology. Journal

IS - 4

ER -

Sunscreens in human plasma and urine after repeated whole-body topical application

Abstract

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