TY - JOUR
T1 - Successful extraction of sperm cells after autologous bone marrow transplant
T2 - a case report
AU - Jacobsen, Frederik M
AU - Fode, Mikkel
AU - Sønksen, Jens
AU - Ohl, Dana A
AU - Jensen, Christian Fuglesang S
PY - 2019/1/30
Y1 - 2019/1/30
N2 - We present a case where microdissection testicular sperm extraction (m.T.E.S.E.) was used in a 36-year-old man after non-Hodgkin T-cell lymphoma treated with 2.5 years of chemotherapy, radiation therapy and autologous bone marrow transplantation (B.M.T.). During m.T.E.S.E. two areas of testis tissue with dilated seminiferous tubules were found both containing several sperm cells. These were cryopreserved and subsequently used for intracytoplasmic sperm injection, resulting in a pregnancy. Although the prognosis for sperm retrieval appears to be poor in most men who have undergone B.M.T., our case demonstrates that this is not an absolute conclusion.
AB - We present a case where microdissection testicular sperm extraction (m.T.E.S.E.) was used in a 36-year-old man after non-Hodgkin T-cell lymphoma treated with 2.5 years of chemotherapy, radiation therapy and autologous bone marrow transplantation (B.M.T.). During m.T.E.S.E. two areas of testis tissue with dilated seminiferous tubules were found both containing several sperm cells. These were cryopreserved and subsequently used for intracytoplasmic sperm injection, resulting in a pregnancy. Although the prognosis for sperm retrieval appears to be poor in most men who have undergone B.M.T., our case demonstrates that this is not an absolute conclusion.
KW - bone marrow transplantation
KW - male infertility
KW - microdissection testicular sperm extraction
KW - Sperm retrieval
UR - http://www.scopus.com/inward/record.url?scp=85060791377&partnerID=8YFLogxK
U2 - 10.1080/21681805.2019.1570329
DO - 10.1080/21681805.2019.1570329
M3 - Journal article
C2 - 30698064
VL - 53
SP - 174
EP - 175
JO - Scandinavian Journal of Urology
JF - Scandinavian Journal of Urology
SN - 2168-1805
IS - 2-3
ER -