@article{114e97a5f1b848d9a82bf24c12498023,
title = "Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida",
abstract = "Anthraquinones have been isolated by bioassay-guided fractionation from Morinda lucida. Structure-activity studies show that an aldehyde group at C-2 and a phenolic hydroxy group at C-3 enhance the activity of the anthraquinones against the growth of Plasmodium falciparum and promastigotes of Leishmania major in vitro.",
keywords = "Animals, Anthraquinones/chemistry, Antimalarials/chemistry, Antiprotozoal Agents/chemistry, Leishmania major/drug effects, Plasmodium falciparum/drug effects, Rubiaceae/chemistry, Structure-Activity Relationship",
author = "Sittie, {A A} and E Lemmich and Olsen, {C E} and L Hviid and A Kharazmi and Nkrumah, {F K} and Christensen, {S B}",
year = "1999",
month = apr,
doi = "10.1055/s-2006-960473",
language = "English",
volume = "65",
pages = "259--61",
journal = "Planta Medica",
issn = "0032-0943",
publisher = "Georg/Thieme Verlag",
number = "3",
}