TY - JOUR
T1 - Structural and Functional Coronary Artery Abnormalities in Patients With Vasospastic Angina Pectoris
AU - Ong, Peter
AU - Aziz, Ahmed
AU - Hansen, Henrik Steen
AU - Prescott, Eva
AU - Athanasiadis, Anastasios
AU - Sechtem, Udo
PY - 2015/6/25
Y1 - 2015/6/25
N2 - Coronary spasm is involved in many clinical scenarios, such as stable angina, acute coronary syndrome, sudden cardiac death, non-ischemic cardiomyopathy, arrhythmia and syncope. In recent years, imaging tools such as computerized tomographic angiography, intravascular ultrasound or optical coherence tomography have been applied to study the coronary pathology in patients with vasospastic angina. Patients with vasospastic angina represent a heterogeneous cohort of patients with regard to the extent of concomitant coronary atherosclerosis. They share the common pathophysiological phenomenon of vascular smooth muscle hyperreactivity leading to spasm caused by various factors that may also overlap. Focal coronary spasm is related to epicardial atherosclerosis and in the presence of obstructive coronary artery disease it may be useful to treat the lesion to prevent further spasm. The aim of this article is to review structural and functional coronary artery abnormalities in patients with vasospastic angina.
AB - Coronary spasm is involved in many clinical scenarios, such as stable angina, acute coronary syndrome, sudden cardiac death, non-ischemic cardiomyopathy, arrhythmia and syncope. In recent years, imaging tools such as computerized tomographic angiography, intravascular ultrasound or optical coherence tomography have been applied to study the coronary pathology in patients with vasospastic angina. Patients with vasospastic angina represent a heterogeneous cohort of patients with regard to the extent of concomitant coronary atherosclerosis. They share the common pathophysiological phenomenon of vascular smooth muscle hyperreactivity leading to spasm caused by various factors that may also overlap. Focal coronary spasm is related to epicardial atherosclerosis and in the presence of obstructive coronary artery disease it may be useful to treat the lesion to prevent further spasm. The aim of this article is to review structural and functional coronary artery abnormalities in patients with vasospastic angina.
U2 - 10.1253/circj.CJ-15-0520
DO - 10.1253/circj.CJ-15-0520
M3 - Journal article
C2 - 26084380
SN - 1346-9843
VL - 79
SP - 1431
EP - 1438
JO - Circulation journal : official journal of the Japanese Circulation Society
JF - Circulation journal : official journal of the Japanese Circulation Society
IS - 7
ER -