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Region Hovedstaden - en del af Københavns Universitetshospital
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Stroke secondary prevention, a non-surgical and non-pharmacological consensus definition: results of a Delphi study

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Cyclic nucleotide phosphodiesterases (PDEs) and endothelial function in ischaemic stroke. A review

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. miRNA-27a-3p and miRNA-222-3p as Novel Modulators of Phosphodiesterase 3a (PDE3A) in Cerebral Microvascular Endothelial Cells

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Home-based aerobic exercise in patients with lacunar stroke: Design of the HITPALS randomized controlled trial

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  • Maggie Lawrence
  • Eric Asaba
  • Elaine Duncan
  • Marie Elf
  • Gunilla Eriksson
  • James Faulkner
  • Susanne Guidetti
  • Birgitta Johansson
  • Christina Kruuse
  • Danielle Lambrick
  • Caitlin Longman
  • Lena von Koch
  • Xu Wang
  • Olive Lennon
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OBJECTIVE: Evidence supporting lifestyle modification in vascular risk reduction is limited, drawn largely from primary prevention studies. To advance the evidence base for non-pharmacological and non-surgical stroke secondary prevention (SSP), empirical research is needed, informed by a consensus-derived definition of SSP. To date, no such definition has been published. We used Delphi methods to generate an evidence-based definition of non-pharmacological and non-surgical SSP.

RESULTS: The 16 participants were members of INSsPiRE (International Network of Stroke Secondary Prevention Researchers), a multidisciplinary group of trialists, academics and clinicians. The Elicitation stage identified 49 key elements, grouped into 3 overarching domains: Risk factors, Education, and Theory before being subjected to iterative stages of elicitation, ranking, discussion, and anonymous voting. In the Action stage, following an experience-based engagement with key stakeholders, a consensus-derived definition, complementing current pharmacological and surgical SSP pathways, was finalised: Non-pharmacological and non-surgical stroke secondary prevention supports and improves long-term health and well-being in everyday life and reduces the risk of another stroke, by drawing from a spectrum of theoretically informed interventions and educational strategies. Interventions to self-manage modifiable lifestyle risk factors are contextualized and individualized to the capacities, needs, and personally meaningful priorities of individuals with stroke and their families.

OriginalsprogEngelsk
TidsskriftBMC Research Notes
Vol/bind12
Udgave nummer1
Sider (fra-til)823
ISSN1756-0500
DOI
StatusUdgivet - 23 dec. 2019

ID: 59115634