Stepwise Development of a Homozygous S80P Substitution in Fks1p, Conferring Echinocandin Resistance in Candida tropicalis

Keyphrases

• Candida Tropicalis 100%
• Echinocandin Resistance 100%
• Stepwise Development 100%
• Caspofungin 50%
• FKS1 50%
• Drug Class 50%
• Amino Acid Substitution 50%
• Acute Lymphoblastic Leukemia 50%
• Homozygous mutation 50%
• Clonal Relationship 50%
• Echinocandins 50%
• Multilocus Sequencing 50%

Biochemistry, Genetics and Molecular Biology

• Echinocandin 100%
• Candida Tropicalis 100%
• Genotyping 50%
• Amino Acid Substitution 50%

Immunology and Microbiology

• Candida Tropicalis 100%
• Genotype 50%
• Amino Acid Substitution 50%