Statin therapy and mortality in HIV-infected individuals; a Danish nationwide population-based cohort study

Line Rasmussen, Gitte Kronborg, Carsten Larsen, Court Pedersen, Jan Gerstoft, Niels Obel

45 Citationer (Scopus)

Abstract

Recent studies have suggested that statins possess diverse immune modulatory and anti-inflammatory properties. As statins might attenuate inflammation, statin therapy has been hypothesized to reduce mortality in HIV-infected individuals. We therefore used a Danish nationwide cohort of HIV-infected individuals to estimate the impact of statin use on mortality before and after a diagnosis of cardiovascular disease, chronic kidney disease or diabetes.
OriginalsprogEngelsk
TidsskriftP L o S One
Vol/bind8
Udgave nummer3
Sider (fra-til)e52828
ISSN1932-6203
DOI
StatusUdgivet - 2013

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