TY - JOUR
T1 - Spread of the FAR-MRSA clone, a fusidic acid- and meticillin-resistant Staphylococcus aureus ST121, Europe, 2014 to 2024
AU - Roer, Louise
AU - Yin, Nicolas
AU - Denis, Olivier
AU - Vendrik, Karuna Ew
AU - Zwittink, Romy D
AU - Notermans, Daan W
AU - Perrin, Monique
AU - Khonyongwa, Kirstin
AU - Tristan, Anne
AU - Youenou, Benjamin
AU - Layer-Nicolaou, Franziska
AU - Werner, Guido
AU - Enger, Hege
AU - Eikrem, Emily Charlotte Henry
AU - Darenberg, Jessica
AU - Mäkitalo, Barbro
AU - Paulsson, Magnus
AU - Björkman, Jonas
AU - Fang, Hong
AU - Hallbäck, Erika Tång
AU - Sundqvist, Martin
AU - Lindholm, Laura
AU - Moganeradj, Kartyk
AU - García-Cobos, Silvia
AU - Cañada-García, Javier E
AU - Holzknecht, Barbara Juliane
AU - Eriksen, Helle Brander
AU - Hoppe, Morten
AU - Bartels, Mette Damkjær
AU - Samaniego Castruita, Jose Alfredo
AU - Urth, Tinna Ravnholt
AU - Larsen, Anders Rhod
AU - Petersen, Andreas
PY - 2025/7
Y1 - 2025/7
N2 - We describe the genetic characteristics of a fusidic acid- and meticillin-resistant Staphylococcus aureus (MRSA) clone widespread in Europe, based on whole genome sequences from 317 isolates. The clone is causing impetigo and other skin and soft tissue infections, primarily in young children. Comparison with publicly available S. aureus ST121 sequences showed that the clone is clearly distinct from previously described ST121 clones. European and other international readers should be aware of the emergence of this community-acquired MRSA clone.
AB - We describe the genetic characteristics of a fusidic acid- and meticillin-resistant Staphylococcus aureus (MRSA) clone widespread in Europe, based on whole genome sequences from 317 isolates. The clone is causing impetigo and other skin and soft tissue infections, primarily in young children. Comparison with publicly available S. aureus ST121 sequences showed that the clone is clearly distinct from previously described ST121 clones. European and other international readers should be aware of the emergence of this community-acquired MRSA clone.
KW - Humans
KW - Methicillin-Resistant Staphylococcus aureus/genetics
KW - Fusidic Acid/pharmacology
KW - Europe/epidemiology
KW - Staphylococcal Infections/epidemiology
KW - Anti-Bacterial Agents/pharmacology
KW - Whole Genome Sequencing
KW - Impetigo/epidemiology
KW - Child
KW - Microbial Sensitivity Tests
KW - Female
KW - Soft Tissue Infections/microbiology
KW - Male
KW - Adult
KW - Child, Preschool
KW - Community-Acquired Infections/epidemiology
KW - Adolescent
KW - Middle Aged
KW - Infant
KW - Staphylococcal Skin Infections/epidemiology
KW - Aged
KW - Young Adult
UR - http://www.scopus.com/inward/record.url?scp=105012052146&partnerID=8YFLogxK
U2 - 10.2807/1560-7917.ES.2025.30.28.2500452
DO - 10.2807/1560-7917.ES.2025.30.28.2500452
M3 - Journal article
C2 - 40682456
SN - 1560-7917
VL - 30
JO - Eurosurveillance
JF - Eurosurveillance
IS - 28
M1 - pii=2500452
ER -