TY - JOUR
T1 - Spontaneous prenatal ductal closure: postnatal diagnosis?
AU - Nygaard, Sissel Irene
AU - Petersen, Olav Bjørn
AU - Garne, Ester
AU - Sørensen, Keld Ejvind
PY - 2008
Y1 - 2008
N2 - Prenatal ductal constriction and closure usually are related to maternal intake of prostaglandin receptor inhibitors during late gestation but may occur spontaneously. This report describes three live-born infants sharing echocardiographic features of spontaneous intrauterine ductal constriction, closure, or both, although only one had a prenatal diagnosis. Interestingly, in addition to severely hypertrophied right ventricles, all three had hyperechogenic tricuspid valve papillary muscles. Two also had mild ascending aorta dilation. These cases raise mechanistic questions because of intrauterine ductal occlusion, bright papillary muscles, and potential dilated ascending aortas.
AB - Prenatal ductal constriction and closure usually are related to maternal intake of prostaglandin receptor inhibitors during late gestation but may occur spontaneously. This report describes three live-born infants sharing echocardiographic features of spontaneous intrauterine ductal constriction, closure, or both, although only one had a prenatal diagnosis. Interestingly, in addition to severely hypertrophied right ventricles, all three had hyperechogenic tricuspid valve papillary muscles. Two also had mild ascending aorta dilation. These cases raise mechanistic questions because of intrauterine ductal occlusion, bright papillary muscles, and potential dilated ascending aortas.
U2 - 10.1007/s00246-008-9269-1
DO - 10.1007/s00246-008-9269-1
M3 - Journal article
C2 - 18779991
SN - 0172-0643
VL - 30
SP - 176
EP - 180
JO - Pediatric Cardiology
JF - Pediatric Cardiology
IS - 2
ER -