@article{0e5627e778124e06837d48f185303a12,
title = "Spironolactone diminishes urinary albumin excretion in patients with type 1 diabetes and microalbuminuria: a randomized placebo-controlled crossover study",
abstract = "Adding aldosterone receptor blockade to standard renoprotective treatment may provide additional renoprotection in patients with overt nephropathy. We expected an impact of spironolactone in early diabetic nephropathy, and for this hypothesis we studied the effect on markers of glomerular and tubular damage in patients with Type 1 diabetes and persistent microalbuminuria.",
keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Albuminuria, Angiotensin Receptor Antagonists, Angiotensin-Converting Enzyme Inhibitors, Antihypertensive Agents, Cross-Over Studies, Diabetes Mellitus, Type 1, Diabetic Nephropathies, Diuretics, Double-Blind Method, Drug Therapy, Combination, Female, Glomerular Filtration Rate, Humans, Male, Middle Aged, Spironolactone, Treatment Outcome, Young Adult",
author = "Nielsen, {S E} and F Persson and E Frandsen and T Sugaya and G Hess and D Zdunek and Shjoedt, {K J} and H-H Parving and Peter Rossing",
note = "{\textcopyright} 2012 The Authors. Diabetic Medicine {\textcopyright} 2012 Diabetes UK.",
year = "2012",
doi = "10.1111/j.1464-5491.2012.03585.x",
language = "English",
volume = "29",
pages = "e184--90",
journal = "Diabet Med",
issn = "0742-3071",
publisher = "Wiley",
number = "8",
}