@article{6b699f013b4e4f2aa379040c958dd757,
title = "Small extracellular vesicles: multi-faceted tools for leukemia immune evasion in vivo",
abstract = "Recently, small extracellular vesicles (sEVs) secreted in vivo from chronic lymphocytic leukemia (CLL) preclinical murine models were characterized. Leukemia microenvironment sEV (LME-sEVs) selectively target CD8+ T-cells, inducing exhaustion and hampering anti-tumor immune response. Additionally, a sEV-related gene expression correlated with patient treatment-free survival, overall survival and clinical parameters.",
keywords = "Animals, CD8-Positive T-Lymphocytes, Extracellular Vesicles/metabolism, Humans, Immune Evasion, Leukemia, Lymphocytic, Chronic, B-Cell/diagnosis, Mice, Tumor Microenvironment, CLL, Small extracellular vesicles, exosomes, sEV-based biomarkers, tumor immune escape, tumor microenvironment",
author = "Ernesto Gargiulo and Elodie Viry and Etienne Moussay and Jerome Paggetti",
note = "{\textcopyright} 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.",
year = "2022",
doi = "10.1080/2162402X.2022.2127507",
language = "English",
volume = "11",
journal = "OncoImmunology",
issn = "2162-4011",
publisher = "Landes Bioscience",
number = "1",
}