Single-shot isotropic diffusion-weighted NMR spectroscopy in the human brain at 7T using tetrahedral encoding

Chloe Najac, Henrik Lundell, Hermien E Kan, Andrew G Webb, Itamar Ronen

Abstract

We propose a single-shot isotropic diffusion-weighted magnetic resonance spectroscopy (DW-MRS) sLASER-based sequence which enables single-shot measurement of metabolite apparent diffusion coefficient (ADC) at relatively short diffusion times and reasonable echo times in the human brain at 7T. Five brain metabolites and water ADC values were measured in two brain regions that differs significantly in white (WM) and grey matter (GM) content. Significantly higher ADCmetabolites and lower ADCwater were observed in WM compared to GM, illustrating microstructural tissue-specific differences.
OriginalsprogEngelsk
TitelProceedings of the 2020 ISMRM & SMRT Virtual Conference & Exhibition
Antal sider3
ForlagThe International Society for Magnetic Resonance in Medicine
Publikationsdato2020
Sider1-3
Artikelnummer0739
StatusUdgivet - 2020
BegivenhedISMRM & SMRT Virtual Conference & Exhibition 2020 - Virtual conference
Varighed: 8 aug. 202014 aug. 2020
https://www.ismrm.org/20m/

Konference

KonferenceISMRM & SMRT Virtual Conference & Exhibition 2020
LokationVirtual conference
Periode08/08/202014/08/2020
Internetadresse

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