Single-shot isotropic diffusion-weighted NMR spectroscopy in the human brain at 7T using tetrahedral encoding

Chloe Najac; Henrik Lundell; Hermien E Kan; Andrew G Webb; Itamar Ronen

Single-shot isotropic diffusion-weighted NMR spectroscopy in the human brain at 7T using tetrahedral encoding

Chloe Najac, Henrik Lundell, Hermien E Kan, Andrew G Webb, Itamar Ronen

Abstrakt

We propose a single-shot isotropic diffusion-weighted magnetic resonance spectroscopy (DW-MRS) sLASER-based sequence which enables single-shot measurement of metabolite apparent diffusion coefficient (ADC) at relatively short diffusion times and reasonable echo times in the human brain at 7T. Five brain metabolites and water ADC values were measured in two brain regions that differs significantly in white (WM) and grey matter (GM) content. Significantly higher ADCmetabolites and lower ADCwater were observed in WM compared to GM, illustrating microstructural tissue-specific differences.

Originalsprog	Engelsk
Titel	Proceedings of the 2020 ISMRM & SMRT Virtual Conference & Exhibition
Antal sider	3
Forlag	The International Society for Magnetic Resonance in Medicine
Publikationsdato	2020
Sider	1-3
Artikelnummer	0739
Status	Udgivet - 2020
Begivenhed	ISMRM & SMRT Virtual Conference & Exhibition 2020 - Virtual conference Varighed: 8 aug. 2020 → 14 aug. 2020 https://www.ismrm.org/20m/

Konference

Konference	ISMRM & SMRT Virtual Conference & Exhibition 2020
Lokation	Virtual conference
Periode	08/08/2020 → 14/08/2020
Internetadresse	https://www.ismrm.org/20m/

Adgang til dokumentet

https://archive.ismrm.org/2020/0739.html

Citationsformater

Najac, C., Lundell, H., Kan, H. E., Webb, A. G., & Ronen, I. (2020). Single-shot isotropic diffusion-weighted NMR spectroscopy in the human brain at 7T using tetrahedral encoding. I Proceedings of the 2020 ISMRM & SMRT Virtual Conference & Exhibition (s. 1-3). [0739] The International Society for Magnetic Resonance in Medicine. https://archive.ismrm.org/2020/0739.html

Single-shot isotropic diffusion-weighted NMR spectroscopy in the human brain at 7T using tetrahedral encoding. / Najac, Chloe; Lundell, Henrik; Kan, Hermien E et al.

Proceedings of the 2020 ISMRM & SMRT Virtual Conference & Exhibition. The International Society for Magnetic Resonance in Medicine, 2020. s. 1-3 0739.

Publikation: Bidrag til bog/antologi/rapport › Konferenceabstrakt i proceedings › Forskning › peer review

Najac, C, Lundell, H, Kan, HE, Webb, AG & Ronen, I 2020, Single-shot isotropic diffusion-weighted NMR spectroscopy in the human brain at 7T using tetrahedral encoding. i Proceedings of the 2020 ISMRM & SMRT Virtual Conference & Exhibition., 0739, The International Society for Magnetic Resonance in Medicine, s. 1-3, ISMRM & SMRT Virtual Conference & Exhibition 2020, 08/08/2020. <https://archive.ismrm.org/2020/0739.html>

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abstract = "We propose a single-shot isotropic diffusion-weighted magnetic resonance spectroscopy (DW-MRS) sLASER-based sequence which enables single-shot measurement of metabolite apparent diffusion coefficient (ADC) at relatively short diffusion times and reasonable echo times in the human brain at 7T. Five brain metabolites and water ADC values were measured in two brain regions that differs significantly in white (WM) and grey matter (GM) content. Significantly higher ADCmetabolites and lower ADCwater were observed in WM compared to GM, illustrating microstructural tissue-specific differences.",

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AU - Ronen, Itamar

PY - 2020

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AB - We propose a single-shot isotropic diffusion-weighted magnetic resonance spectroscopy (DW-MRS) sLASER-based sequence which enables single-shot measurement of metabolite apparent diffusion coefficient (ADC) at relatively short diffusion times and reasonable echo times in the human brain at 7T. Five brain metabolites and water ADC values were measured in two brain regions that differs significantly in white (WM) and grey matter (GM) content. Significantly higher ADCmetabolites and lower ADCwater were observed in WM compared to GM, illustrating microstructural tissue-specific differences.

M3 - Conference abstract in proceedings

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ER -

Single-shot isotropic diffusion-weighted NMR spectroscopy in the human brain at 7T using tetrahedral encoding

Abstrakt

Konference

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Citationsformater