Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment

Jayant S. Vaidya*, Max Bulsara, Michael Baum, Jeffrey S. Tobias, Frederik Wenz, Samuele Massarut, Steffi Pigorsch, Michael Alvarado, Michael Douek, Christobel Saunders, Henrik L. Flyger, Wolfgang Eiermann, Chris Brew-Graves, Norman R. Williams, Ingrid Potyka, Nicholas Roberts, Marcelle Bernstein, Douglas Brown, Elena Sperk, Siobhan LawsMarc Sütterlin, Tammy Corica, Steinar Lundgren, Dennis Holmes, Lorenzo Vinante, Fernando Bozza, Montserrat Pazos, Magali Le Blanc-Onfroy, Günther Gruber, Wojciech Polkowski, Konstantin J. Dedes, Marcus Niewald, Jens Blohmer, David McCready, Richard Hoefer, Pond Kelemen, Gloria Petralia, Mary Falzon, David J. Joseph, on behalf of the TARGIT-A trial authors

*Corresponding author af dette arbejde
15 Citationer (Scopus)

Abstract

In the randomised TARGIT-A trial, risk-adapted targeted intraoperative radiotherapy (TARGIT-IORT) during lumpectomy was non-inferior to whole-breast external beam radiotherapy, for local recurrence. In the long-term, no difference was found in any breast cancer outcome, whereas there were fewer deaths from non-breast-cancer causes. TARGIT-IORT should be included in pre-operative consultations with eligible patients.

OriginalsprogEngelsk
TidsskriftBritish Journal of Cancer
Vol/bind124
Udgave nummer9
Sider (fra-til)1469–1474
Antal sider6
ISSN0007-0920
DOI
StatusUdgivet - apr. 2021

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