Should dosing of rocuronium in obese patients be based on ideal or corrected body weight?

Christian S Meyhoff; Jørgen Lund; Morten T Jenstrup; Casper Claudius; Anne M Sørensen; Jørgen Viby-Mogensen; Lars S Rasmussen

doi:10.1213/ane.0b013e3181b0826a

Should dosing of rocuronium in obese patients be based on ideal or corrected body weight?

Christian S Meyhoff, Jørgen Lund, Morten T Jenstrup, Casper Claudius, Anne M Sørensen, Jørgen Viby-Mogensen, Lars S Rasmussen

98 Citationer (Scopus)

Abstract

Pharmacokinetic studies in obese patients suggest that dosing of rocuronium should be based on ideal body weight (IBW). This may, however, result in a prolonged onset time or compromised conditions for tracheal intubation. In this study, we compared onset time, conditions for tracheal intubation, and duration of action in obese patients when the intubation dose of rocuronium was based on three different weight corrections.

Originalsprog	Engelsk
Tidsskrift	Anesthesia and Analgesia
Vol/bind	109
Udgave nummer	3
Sider (fra-til)	787-92
Antal sider	6
ISSN	0003-2999
DOI	https://doi.org/10.1213/ane.0b013e3181b0826a
Status	Udgivet - sep. 2009

Adgang til dokumentet

10.1213/ane.0b013e3181b0826a

Citationsformater

@article{17625cae36b44b77aca204bce4a183e5,

title = "Should dosing of rocuronium in obese patients be based on ideal or corrected body weight?",

abstract = "Pharmacokinetic studies in obese patients suggest that dosing of rocuronium should be based on ideal body weight (IBW). This may, however, result in a prolonged onset time or compromised conditions for tracheal intubation. In this study, we compared onset time, conditions for tracheal intubation, and duration of action in obese patients when the intubation dose of rocuronium was based on three different weight corrections.",

keywords = "Adult, Androstanols, Anesthesia Recovery Period, Anesthetics, Intravenous, Body Mass Index, Body Weight, Female, Gastric Bypass, Humans, Male, Middle Aged, Neuromuscular Nondepolarizing Agents, Obesity, Piperidines, Propofol",

author = "Meyhoff, {Christian S} and J{\o}rgen Lund and Jenstrup, {Morten T} and Casper Claudius and S{\o}rensen, {Anne M} and J{\o}rgen Viby-Mogensen and Rasmussen, {Lars S}",

year = "2009",

month = sep,

doi = "10.1213/ane.0b013e3181b0826a",

language = "English",

volume = "109",

pages = "787--92",

journal = "Anesthesia and Analgesia",

issn = "0003-2999",