Short and long term mortality and causes of death in HIV/TB patients in Europe

Daria Podlekareva, Alexander M Panteleev, Daniel Grint, Frank A Post, Jose M Miro, Mathias Bruyand, Hansjakob Furrer, Niels Obel, Enrico Girardi, Anna Vasilenko, Marcelo H Losso, Alejandro Arenas-Pinto, Joan Caylá, Aza Rakhmanova, Indra Zeltina, Anne Marie Werlinrud, Jens D Lundgren, Amanda Mocroft, Ole Kirk, the HIV/TB study group

    32 Citationer (Scopus)

    Abstract

    Mortality of HIV/TB patients in Eastern Europe (EE) is high. Little is known about their causes of death (COD).To assess and compare mortality rates and COD in HIV/TB patients across EE and Western Europe and Argentina (WEA) in an international cohort study.Mortality rates and COD were analysed by time from TB diagnosis (12 months) in 1078 consecutive HIV-/TB patients. Factors associated with TB-related death were examined in multivariate Poisson regression analysis.347 patients died during 2625 PYFU. Mortality in EE was 3-9-fold higher than in WEA. TB was the main COD in EE in 80%, 66% and 61% of patients who died 12 months after TB diagnosis, compared to 50%, 0% and 15% in the same time periods in WEA (p
    OriginalsprogEngelsk
    TidsskriftEuropean Respiratory Journal
    Vol/bind43
    Udgave nummer1
    Sider (fra-til)166-177
    ISSN0903-1936
    DOI
    StatusUdgivet - 2014

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