Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022

Ruben H de Kleine; Willem S Lexmond; Gustav Buescher; Ekkehard Sturm; Deidre Kelly; Ansgar W Lohse; Dominic Lenz; Marianne Hørby Jørgensen; European Reference Network for hepatological diseases (ERN-LIVER); Marianne Hørby Jørgensen

doi:10.2807/1560-7917.ES.2022.27.19.2200369

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022

Ruben H de Kleine, Willem S Lexmond, Gustav Buescher, Ekkehard Sturm, Deidre Kelly, Ansgar W Lohse, Dominic Lenz, Marianne Hørby Jørgensen, European Reference Network for hepatological diseases (ERN-LIVER), Marianne Hørby Jørgensen

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Abstract

To detect potential concern about severe acute hepatitis in children, we conducted a survey among 50 ERN RARE-LIVER centres. By 26 April 2022, 34 centres, including 25 transplant centres, reported an estimated median of 3-5, 0-2 and 3-5 cases in 2021, 2020 and 2019 and a mean of 2 (range: 0-8) cases between January and April 2022 (mean in 10 large liver transplant centres: 3). Twelve centres reported suspicion of an increase, but no rise.

Originalsprog	Engelsk
Artikelnummer	2200369
Tidsskrift	Eurosurveillance
Vol/bind	27
Udgave nummer	19
ISSN	1560-7917
DOI	https://doi.org/10.2807/1560-7917.ES.2022.27.19.2200369
Status	Udgivet - 1 maj 2022

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10.2807/1560-7917.ES.2022.27.19.2200369

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de Kleine, R. H., Lexmond, W. S., Buescher, G., Sturm, E., Kelly, D., Lohse, A. W., Lenz, D., Hørby Jørgensen, M., European Reference Network for hepatological diseases (ERN-LIVER), & Jørgensen, M. H. (2022). Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022. Eurosurveillance, 27(19), Artikel 2200369. https://doi.org/10.2807/1560-7917.ES.2022.27.19.2200369

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022. / de Kleine, Ruben H; Lexmond, Willem S; Buescher, Gustav et al.
I: Eurosurveillance, Bind 27, Nr. 19, 2200369, 01.05.2022.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

de Kleine, RH, Lexmond, WS, Buescher, G, Sturm, E, Kelly, D, Lohse, AW, Lenz, D, Hørby Jørgensen, M, European Reference Network for hepatological diseases (ERN-LIVER) & Jørgensen, MH 2022, 'Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022', Eurosurveillance, bind 27, nr. 19, 2200369. https://doi.org/10.2807/1560-7917.ES.2022.27.19.2200369

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abstract = "To detect potential concern about severe acute hepatitis in children, we conducted a survey among 50 ERN RARE-LIVER centres. By 26 April 2022, 34 centres, including 25 transplant centres, reported an estimated median of 3-5, 0-2 and 3-5 cases in 2021, 2020 and 2019 and a mean of 2 (range: 0-8) cases between January and April 2022 (mean in 10 large liver transplant centres: 3). Twelve centres reported suspicion of an increase, but no rise.",

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Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022

Abstract

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