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Serum urate as a proposed surrogate outcome measure in gout trials: From the OMERACT working group

Publikation: Bidrag til tidsskriftReviewpeer review

Harvard

Morillon, MB, Christensen, R, Singh, JA, Dalbeth, N, Saag, K, Taylor, WJ, Neogi, T, Kennedy, MA, Pedersen, BM, McCarthy, GM, Shea, B, Diaz-Torne, C, Tedeschi, SK, Grainger, R, Abhishek, A, Gaffo, A, Nielsen, SM, Noerup, A, Simon, LS, Lassere, M, Tugwell, P, Stamp, LK & Gout Working Group, FTO 2021, 'Serum urate as a proposed surrogate outcome measure in gout trials: From the OMERACT working group', Seminars in Arthritis and Rheumatism, bind 51, nr. 6, s. 1378-1385. https://doi.org/10.1016/j.semarthrit.2021.11.004

APA

Morillon, M. B., Christensen, R., Singh, J. A., Dalbeth, N., Saag, K., Taylor, W. J., Neogi, T., Kennedy, M. A., Pedersen, B. M., McCarthy, G. M., Shea, B., Diaz-Torne, C., Tedeschi, S. K., Grainger, R., Abhishek, A., Gaffo, A., Nielsen, S. M., Noerup, A., Simon, L. S., ... Gout Working Group, F. T. O. (2021). Serum urate as a proposed surrogate outcome measure in gout trials: From the OMERACT working group. Seminars in Arthritis and Rheumatism, 51(6), 1378-1385. https://doi.org/10.1016/j.semarthrit.2021.11.004

CBE

Morillon MB, Christensen R, Singh JA, Dalbeth N, Saag K, Taylor WJ, Neogi T, Kennedy MA, Pedersen BM, McCarthy GM, Shea B, Diaz-Torne C, Tedeschi SK, Grainger R, Abhishek A, Gaffo A, Nielsen SM, Noerup A, Simon LS, Lassere M, Tugwell P, Stamp LK, Gout Working Group FTO. 2021. Serum urate as a proposed surrogate outcome measure in gout trials: From the OMERACT working group. Seminars in Arthritis and Rheumatism. 51(6):1378-1385. https://doi.org/10.1016/j.semarthrit.2021.11.004

MLA

Vancouver

Author

Morillon, Melanie Birger ; Christensen, Robin ; Singh, Jasvinder A ; Dalbeth, Nicola ; Saag, Kenneth ; Taylor, William J ; Neogi, Tuhina ; Kennedy, Martin A ; Pedersen, Birthe M ; McCarthy, Geraldine M ; Shea, Beverley ; Diaz-Torne, Cesar ; Tedeschi, Sara K ; Grainger, Rebecca ; Abhishek, Abhishek ; Gaffo, Angelo ; Nielsen, Sabrina Mai ; Noerup, Alexander ; Simon, Lee S ; Lassere, Marissa ; Tugwell, Peter ; Stamp, Lisa K ; Gout Working Group, For The Omeract. / Serum urate as a proposed surrogate outcome measure in gout trials : From the OMERACT working group. I: Seminars in Arthritis and Rheumatism. 2021 ; Bind 51, Nr. 6. s. 1378-1385.

Bibtex

@article{162d6365f8974660ba8f334c9be31e87,
title = "Serum urate as a proposed surrogate outcome measure in gout trials: From the OMERACT working group",
abstract = "Serum urate (SU) is the most common primary efficacy outcome in trials of urate-lowering therapies for gout. Despite this, it is not formally considered a validated surrogate outcome. In this paper we will outline the definitions of biomarkers and surrogate outcome measures, respectively as well as the available frameworks and challenges in the assessment of the validity of serum urate as a surrogate in gout (i.e. a reasonable replacement for gout symptoms).",
author = "Morillon, {Melanie Birger} and Robin Christensen and Singh, {Jasvinder A} and Nicola Dalbeth and Kenneth Saag and Taylor, {William J} and Tuhina Neogi and Kennedy, {Martin A} and Pedersen, {Birthe M} and McCarthy, {Geraldine M} and Beverley Shea and Cesar Diaz-Torne and Tedeschi, {Sara K} and Rebecca Grainger and Abhishek Abhishek and Angelo Gaffo and Nielsen, {Sabrina Mai} and Alexander Noerup and Simon, {Lee S} and Marissa Lassere and Peter Tugwell and Stamp, {Lisa K} and {Gout Working Group}, {For The Omeract}",
note = "Copyright {\textcopyright} 2021 Elsevier Inc. All rights reserved.",
year = "2021",
month = dec,
doi = "10.1016/j.semarthrit.2021.11.004",
language = "English",
volume = "51",
pages = "1378--1385",
journal = "Seminars in Arthritis and Rheumatism",
issn = "0049-0172",
publisher = "W.B./Saunders Co",
number = "6",

}

RIS

TY - JOUR

T1 - Serum urate as a proposed surrogate outcome measure in gout trials

T2 - From the OMERACT working group

AU - Morillon, Melanie Birger

AU - Christensen, Robin

AU - Singh, Jasvinder A

AU - Dalbeth, Nicola

AU - Saag, Kenneth

AU - Taylor, William J

AU - Neogi, Tuhina

AU - Kennedy, Martin A

AU - Pedersen, Birthe M

AU - McCarthy, Geraldine M

AU - Shea, Beverley

AU - Diaz-Torne, Cesar

AU - Tedeschi, Sara K

AU - Grainger, Rebecca

AU - Abhishek, Abhishek

AU - Gaffo, Angelo

AU - Nielsen, Sabrina Mai

AU - Noerup, Alexander

AU - Simon, Lee S

AU - Lassere, Marissa

AU - Tugwell, Peter

AU - Stamp, Lisa K

AU - Gout Working Group, For The Omeract

N1 - Copyright © 2021 Elsevier Inc. All rights reserved.

PY - 2021/12

Y1 - 2021/12

N2 - Serum urate (SU) is the most common primary efficacy outcome in trials of urate-lowering therapies for gout. Despite this, it is not formally considered a validated surrogate outcome. In this paper we will outline the definitions of biomarkers and surrogate outcome measures, respectively as well as the available frameworks and challenges in the assessment of the validity of serum urate as a surrogate in gout (i.e. a reasonable replacement for gout symptoms).

AB - Serum urate (SU) is the most common primary efficacy outcome in trials of urate-lowering therapies for gout. Despite this, it is not formally considered a validated surrogate outcome. In this paper we will outline the definitions of biomarkers and surrogate outcome measures, respectively as well as the available frameworks and challenges in the assessment of the validity of serum urate as a surrogate in gout (i.e. a reasonable replacement for gout symptoms).

UR - http://www.scopus.com/inward/record.url?scp=85120337109&partnerID=8YFLogxK

U2 - 10.1016/j.semarthrit.2021.11.004

DO - 10.1016/j.semarthrit.2021.11.004

M3 - Review

C2 - 34839932

VL - 51

SP - 1378

EP - 1385

JO - Seminars in Arthritis and Rheumatism

JF - Seminars in Arthritis and Rheumatism

SN - 0049-0172

IS - 6

ER -

ID: 70330157