Serum markers of liver fibrosis: combining the BIPED classification and the neo-epitope approach in the development of new biomarkers

Sanne Skovgård Veidal; Anne-Christine Bay-Jensen; Gervais Tougas; Morten Asser Karsdal; Ben Vainer

doi:10.3233/DMA-2010-0678

Serum markers of liver fibrosis: combining the BIPED classification and the neo-epitope approach in the development of new biomarkers

Sanne Skovgård Veidal, Anne-Christine Bay-Jensen, Gervais Tougas, Morten Asser Karsdal, Ben Vainer

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Abstract

Fibrosis is a central histological feature of chronic liver diseases and is characterized by the accumulation and reorganization of the extracellular matrix. The gold standard for assessment of fibrosis is histological evaluation of a percutaneous liver biopsy. Albeit a considerable effort have been invested in finding alternative non-invasive approaches, these have not been sufficiently successful to replace biopsy assessment.

Originalsprog	Engelsk
Tidsskrift	Disease Markers
Vol/bind	28
Udgave nummer	1
Sider (fra-til)	15-28
Antal sider	14
DOI	https://doi.org/10.3233/DMA-2010-0678
Status	Udgivet - 1 jan. 2010

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10.3233/DMA-2010-0678

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833336/

Citationsformater

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abstract = "Fibrosis is a central histological feature of chronic liver diseases and is characterized by the accumulation and reorganization of the extracellular matrix. The gold standard for assessment of fibrosis is histological evaluation of a percutaneous liver biopsy. Albeit a considerable effort have been invested in finding alternative non-invasive approaches, these have not been sufficiently successful to replace biopsy assessment.",

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AU - Veidal, Sanne Skovgård

AU - Bay-Jensen, Anne-Christine

AU - Tougas, Gervais

AU - Karsdal, Morten Asser

AU - Vainer, Ben

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Fibrosis is a central histological feature of chronic liver diseases and is characterized by the accumulation and reorganization of the extracellular matrix. The gold standard for assessment of fibrosis is histological evaluation of a percutaneous liver biopsy. Albeit a considerable effort have been invested in finding alternative non-invasive approaches, these have not been sufficiently successful to replace biopsy assessment.

AB - Fibrosis is a central histological feature of chronic liver diseases and is characterized by the accumulation and reorganization of the extracellular matrix. The gold standard for assessment of fibrosis is histological evaluation of a percutaneous liver biopsy. Albeit a considerable effort have been invested in finding alternative non-invasive approaches, these have not been sufficiently successful to replace biopsy assessment.

U2 - 10.3233/DMA-2010-0678

DO - 10.3233/DMA-2010-0678

M3 - Journal article

C2 - 20164543

SN - 1875-8630

VL - 28

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JO - Disease Markers

JF - Disease Markers

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ER -

Serum markers of liver fibrosis: combining the BIPED classification and the neo-epitope approach in the development of new biomarkers

Abstract

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