Serum levels of advanced glycation end products are associated with left ventricular diastolic function in patients with type 1 diabetes

T J Berg, O Snorgaard, J Faber, P A Torjesen, P Hildebrandt, J Mehlsen, K F Hanssen

191 Citationer (Scopus)

Abstract

Impairment of left ventricular diastolic function, possibly caused by increased collagen cross-linking of the cardiac muscle, is common in patients with type 1 diabetes even without coronary artery disease. Advanced glycation end products (AGEs) cross-link tissue collagen and are found within myocardial fibers. The aim of this study was to examine for a possible association between circulating AGEs and left ventricular cardiac function.
OriginalsprogEngelsk
TidsskriftDiabetes Care
Vol/bind22
Udgave nummer7
Sider (fra-til)1186-90
Antal sider5
ISSN0149-5992
StatusUdgivet - 1 jul. 1999

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