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Region Hovedstaden - en del af Københavns Universitetshospital
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Serum concentrations of free and total insulin-like growth factor-I, IGF binding proteins -1 and -3 and IGFBP-3 protease activity in boys with normal or precocious puberty

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Circulating IGF-I and IGF binding protein-3 (IGFBP-3) levels both increase in puberty where growth velocity is high. The amount of free IGF-I is dependent on the IGF-I level and on the concentrations of the specific IGFBPs. Furthermore, IGFBP-3 proteolysis regulates the bioavailability of IGF-I. However, the concentration of free IGF-I and possible IGFBP-3 proteolytic activity in puberty has not previously been studied.
OriginalsprogEngelsk
TidsskriftClinical Endocrinology
Vol/bind44
Udgave nummer5
Sider (fra-til)515-23
Antal sider9
ISSN0300-0664
StatusUdgivet - 1996

ID: 36944860