Self-experience in the early phases of schizophrenia: 5-year follow-up of the Copenhagen Prodromal Study

Josef Parnas, Andrea Raballo, Peter Handest, Lennart Jansson, Anne Vollmer-Larsen, Ditte Saebye

    140 Citationer (Scopus)

    Abstract

    Despite the avalanche of empirical data on prodromal/"at risk" conditions, the essential aspects of the vulnerability to the schizophrenia spectrum remain largely unaddressed. We report here the results of the Copenhagen Schizophrenia Prodromal Study, a prospective, observational study of first admission patients in putative state of beginning psychosis (N=151) with a follow-up length of 60 months. At follow-up, the rate of conversion to schizophrenia spectrum diagnosis was 37%, whereas the conversion rate from schizotypal disorder to schizophrenia was 25%. High levels of perplexity and self-disorders baseline scores yielded the best prediction of the subsequent development of schizophrenia spectrum disorders. Escalating transitions within the spectrum (i.e., from schizotypal disorder to schizophrenia) were not associated to any candidate psychopathological predictor.
    OriginalsprogEngelsk
    TidsskriftWorld Psychiatry
    Vol/bind10
    Udgave nummer3
    Sider (fra-til)200-4
    Antal sider5
    ISSN1723-8617
    StatusUdgivet - 1 okt. 2011

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