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Secondhand cigarette smoke exposure causes upregulation of cerebrovascular 5-HT(1) (B) receptors via the Raf/ERK/MAPK pathway in rats

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@article{5babbb75ec2d4670a1ce4715ef46ce31,
title = "Secondhand cigarette smoke exposure causes upregulation of cerebrovascular 5-HT(1) (B) receptors via the Raf/ERK/MAPK pathway in rats",
abstract = "Cigarette smoke exposure increases the risk of stroke. Upregulation of 5-hydroxytryptamine 1B (5-HT(1) (B) ) receptors is associated with the pathogenesis of cerebral ischaemia. This study examined the hypothesis that the expression of 5-HT(1) (B) receptors is altered in brain vessels after secondhand smoke (SHS) exposure.",
keywords = "Animals, Cerebrovascular Circulation, Extracellular Signal-Regulated MAP Kinases, Gene Expression, Indoles, MAP Kinase Kinase Kinases, MAP Kinase Signaling System, Male, Phenols, Phosphorylation, Rats, Rats, Sprague-Dawley, Receptor, Serotonin, 5-HT1B, Serotonin, Serotonin Receptor Agonists, Tobacco Smoke Pollution, Up-Regulation, Vasoconstriction",
author = "L Cao and Xu, {C B} and Y Zhang and Cao, {Y X} and L Edvinsson",
note = "{\textcopyright} 2012 The Authors Acta Physiologica {\textcopyright} 2012 Scandinavian Physiological Society.",
year = "2013",
month = jan,
doi = "10.1111/j.1748-1716.2012.02478.x",
language = "English",
volume = "207",
pages = "183--93",
journal = "Acta Physiologica",
issn = "1748-1708",
publisher = "Wiley-Blackwell Publishing Ltd",
number = "1",

}

RIS

TY - JOUR

T1 - Secondhand cigarette smoke exposure causes upregulation of cerebrovascular 5-HT(1) (B) receptors via the Raf/ERK/MAPK pathway in rats

AU - Cao, L

AU - Xu, C B

AU - Zhang, Y

AU - Cao, Y X

AU - Edvinsson, L

N1 - © 2012 The Authors Acta Physiologica © 2012 Scandinavian Physiological Society.

PY - 2013/1

Y1 - 2013/1

N2 - Cigarette smoke exposure increases the risk of stroke. Upregulation of 5-hydroxytryptamine 1B (5-HT(1) (B) ) receptors is associated with the pathogenesis of cerebral ischaemia. This study examined the hypothesis that the expression of 5-HT(1) (B) receptors is altered in brain vessels after secondhand smoke (SHS) exposure.

AB - Cigarette smoke exposure increases the risk of stroke. Upregulation of 5-hydroxytryptamine 1B (5-HT(1) (B) ) receptors is associated with the pathogenesis of cerebral ischaemia. This study examined the hypothesis that the expression of 5-HT(1) (B) receptors is altered in brain vessels after secondhand smoke (SHS) exposure.

KW - Animals

KW - Cerebrovascular Circulation

KW - Extracellular Signal-Regulated MAP Kinases

KW - Gene Expression

KW - Indoles

KW - MAP Kinase Kinase Kinases

KW - MAP Kinase Signaling System

KW - Male

KW - Phenols

KW - Phosphorylation

KW - Rats

KW - Rats, Sprague-Dawley

KW - Receptor, Serotonin, 5-HT1B

KW - Serotonin

KW - Serotonin Receptor Agonists

KW - Tobacco Smoke Pollution

KW - Up-Regulation

KW - Vasoconstriction

U2 - 10.1111/j.1748-1716.2012.02478.x

DO - 10.1111/j.1748-1716.2012.02478.x

M3 - Journal article

C2 - 22883081

VL - 207

SP - 183

EP - 193

JO - Acta Physiologica

JF - Acta Physiologica

SN - 1748-1708

IS - 1

ER -

ID: 43093554