Secondhand cigarette smoke exposure causes upregulation of cerebrovascular 5-HT(1) (B) receptors via the Raf/ERK/MAPK pathway in rats

L Cao, C B Xu, Y Zhang, Y X Cao, L Edvinsson

18 Citationer (Scopus)

Abstract

Cigarette smoke exposure increases the risk of stroke. Upregulation of 5-hydroxytryptamine 1B (5-HT(1) (B) ) receptors is associated with the pathogenesis of cerebral ischaemia. This study examined the hypothesis that the expression of 5-HT(1) (B) receptors is altered in brain vessels after secondhand smoke (SHS) exposure.
OriginalsprogEngelsk
TidsskriftActa physiologica (Oxford, England)
Vol/bind207
Udgave nummer1
Sider (fra-til)183-93
Antal sider11
ISSN1748-1708
DOI
StatusUdgivet - jan. 2013

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