Samfundserhvervet pneumoni--behandling

Ljubica Vukelic Andersen; Birgitte Brock; Preben Jakobsen; Lars Peter Nielsen

Samfundserhvervet pneumoni--behandling

Ljubica Vukelic Andersen, Birgitte Brock, Preben Jakobsen, Lars Peter Nielsen

1 Citationer (Scopus)

Abstract

Penicillin is the drug of choice for treatment of community-acquired pneumonia (CAP) in Denmark. The primary determinant for therapeutic activity of penicillin is ''penicillin time'' (T>MIC), i.e. time with penicillin concentration above minimum inhibitory concentration. Eradication of S. pneumoniae requires T>MIC above 40-50%. The second determinant for therapeutic activity is the ratio between maximum penicillin concentration in serum and MIC (Cmax/MIC). Considering penicillin pharmacokinetics, intravenous penicillin 2 million units four times a day is recommended as empirical treatment of CAP.

Bidragets oversatte titel	Treatment of community-acquired pneumonia--treatment
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	170
Udgave nummer	3
Sider (fra-til)	127-30
Antal sider	4
ISSN	0041-5782
Status	Udgivet - 14 jan. 2008
Udgivet eksternt	Ja

Emneord

Community-Acquired Infections
Humans
Injections, Intravenous
Microbial Sensitivity Tests
Penicillins
Pneumonia, Pneumococcal
Streptococcus pneumoniae

Adgang til dokumentet

http://ugeskriftet.dk/videnskab/samfundserhvervet-pneumoni-behandling

Andre filer og links

Link to publication in Scopus

Citationsformater

@article{2f5190d40c534383a2b3e6cd15718a16,

title = "Samfundserhvervet pneumoni--behandling",

abstract = "Penicillin is the drug of choice for treatment of community-acquired pneumonia (CAP) in Denmark. The primary determinant for therapeutic activity of penicillin is ''penicillin time'' (T>MIC), i.e. time with penicillin concentration above minimum inhibitory concentration. Eradication of S. pneumoniae requires T>MIC above 40-50\%. The second determinant for therapeutic activity is the ratio between maximum penicillin concentration in serum and MIC (Cmax/MIC). Considering penicillin pharmacokinetics, intravenous penicillin 2 million units four times a day is recommended as empirical treatment of CAP.",

keywords = "Community-Acquired Infections, Humans, Injections, Intravenous, Microbial Sensitivity Tests, Penicillins, Pneumonia, Pneumococcal, Streptococcus pneumoniae, English Abstract, Journal Article, Review",

author = "Andersen, \{Ljubica Vukelic\} and Birgitte Brock and Preben Jakobsen and Nielsen, \{Lars Peter\}",

year = "2008",

month = jan,

day = "14",

language = "Dansk",

volume = "170",

pages = "127--30",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "3",

}

TY - JOUR

T1 - Samfundserhvervet pneumoni--behandling

AU - Andersen, Ljubica Vukelic

AU - Brock, Birgitte

AU - Jakobsen, Preben

AU - Nielsen, Lars Peter

PY - 2008/1/14

Y1 - 2008/1/14

N2 - Penicillin is the drug of choice for treatment of community-acquired pneumonia (CAP) in Denmark. The primary determinant for therapeutic activity of penicillin is ''penicillin time'' (T>MIC), i.e. time with penicillin concentration above minimum inhibitory concentration. Eradication of S. pneumoniae requires T>MIC above 40-50%. The second determinant for therapeutic activity is the ratio between maximum penicillin concentration in serum and MIC (Cmax/MIC). Considering penicillin pharmacokinetics, intravenous penicillin 2 million units four times a day is recommended as empirical treatment of CAP.

AB - Penicillin is the drug of choice for treatment of community-acquired pneumonia (CAP) in Denmark. The primary determinant for therapeutic activity of penicillin is ''penicillin time'' (T>MIC), i.e. time with penicillin concentration above minimum inhibitory concentration. Eradication of S. pneumoniae requires T>MIC above 40-50%. The second determinant for therapeutic activity is the ratio between maximum penicillin concentration in serum and MIC (Cmax/MIC). Considering penicillin pharmacokinetics, intravenous penicillin 2 million units four times a day is recommended as empirical treatment of CAP.

KW - Community-Acquired Infections

KW - Humans

KW - Injections, Intravenous

KW - Microbial Sensitivity Tests

KW - Penicillins

KW - Pneumonia, Pneumococcal

KW - Streptococcus pneumoniae

KW - English Abstract

KW - Journal Article

KW - Review

UR - https://www.scopus.com/pages/publications/38749113796

M3 - Tidsskriftartikel

C2 - 18208726

SN - 0041-5782

VL - 170

SP - 127

EP - 130

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 3

ER -

Samfundserhvervet pneumoni--behandling

Abstract

Emneord

Adgang til dokumentet

Andre filer og links

Fingeraftryk

Citationsformater