S-adenosyl-L-methionine for alcoholic liver diseases

A Rambaldi; C Gluud

doi:10.1002/14651858.CD002235

S-adenosyl-L-methionine for alcoholic liver diseases

A Rambaldi, C Gluud

Copenhagen Trial Unit Rigshospitalet

52 Citationer (Scopus)

Abstract

Alcohol is a major cause of liver disease in the Western world today. S-adenosyl-L-methionine (SAMe) acts as a methyl donor for all known biological methylation reactions and participates in the synthesis of glutathione, the main cellular anti-oxidant. Randomised clinical trials have addressed the question whether SAMe has any efficacy in patients with alcoholic liver diseases.

Originalsprog	Engelsk
Tidsskrift	Cochrane Database of Systematic Reviews
Udgave nummer	4
Sider (fra-til)	CD002235
ISSN	1469-493X
DOI	https://doi.org/10.1002/14651858.CD002235
Status	Udgivet - 2001

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10.1002/14651858.CD002235

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title = "S-adenosyl-L-methionine for alcoholic liver diseases",

abstract = "Alcohol is a major cause of liver disease in the Western world today. S-adenosyl-L-methionine (SAMe) acts as a methyl donor for all known biological methylation reactions and participates in the synthesis of glutathione, the main cellular anti-oxidant. Randomised clinical trials have addressed the question whether SAMe has any efficacy in patients with alcoholic liver diseases.",

keywords = "Humans, Liver Diseases, Alcoholic, Randomized Controlled Trials as Topic, S-Adenosylmethionine",

author = "A Rambaldi and C Gluud",

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journal = "Cochrane Database of Systematic Reviews",

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T1 - S-adenosyl-L-methionine for alcoholic liver diseases

AU - Rambaldi, A

AU - Gluud, C

PY - 2001

Y1 - 2001

N2 - Alcohol is a major cause of liver disease in the Western world today. S-adenosyl-L-methionine (SAMe) acts as a methyl donor for all known biological methylation reactions and participates in the synthesis of glutathione, the main cellular anti-oxidant. Randomised clinical trials have addressed the question whether SAMe has any efficacy in patients with alcoholic liver diseases.

AB - Alcohol is a major cause of liver disease in the Western world today. S-adenosyl-L-methionine (SAMe) acts as a methyl donor for all known biological methylation reactions and participates in the synthesis of glutathione, the main cellular anti-oxidant. Randomised clinical trials have addressed the question whether SAMe has any efficacy in patients with alcoholic liver diseases.

KW - Humans

KW - Liver Diseases, Alcoholic

KW - Randomized Controlled Trials as Topic

KW - S-Adenosylmethionine

UR - https://www.scopus.com/pages/publications/0009804859

U2 - 10.1002/14651858.CD002235

DO - 10.1002/14651858.CD002235

M3 - Journal article

C2 - 11687153

SN - 1469-493X

SP - CD002235

JO - Cochrane Database of Systematic Reviews

JF - Cochrane Database of Systematic Reviews

IS - 4

ER -

S-adenosyl-L-methionine for alcoholic liver diseases

Abstract

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