Role of PGC-1α in exercise training- and resveratrol-induced prevention of age-associated inflammation

Jesper Olesen, Stine Ringholm, Maja Munk Nielsen, Christina Tingbjerg Brandt, Jesper T Pedersen, Jens F Halling, Laurie J Goodyear, Henriette Pilegaard

    35 Citationer (Scopus)

    Abstract

    Age-related metabolic diseases are often associated with low-grade inflammation. The aim of the present study was to investigate the role of the transcriptional co-activator PGC-1α in the potential beneficial effects of exercise training and/or resveratrol in the prevention of age-associated low-grade inflammation. To address this, a long-term voluntary exercise training and resveratrol supplementation study was conducted.
    OriginalsprogEngelsk
    TidsskriftExperimental Gerontology
    Vol/bind48
    Udgave nummer11
    Sider (fra-til)1274-84
    Antal sider11
    ISSN0531-5565
    DOI
    StatusUdgivet - nov. 2013

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