Robustness assessments are needed to reduce bias in meta-analyses that include zero-event randomized trials

F Keus; J Wetterslev; C Gluud; H G Gooszen; C J H M van Laarhoven

doi:10.1038/ajg.2008.22

Robustness assessments are needed to reduce bias in meta-analyses that include zero-event randomized trials

F Keus, J Wetterslev, C Gluud, H G Gooszen, C J H M van Laarhoven

Copenhagen Trial Unit Rigshospitalet

81 Citationer (Scopus)

Abstract

Meta-analysis of randomized trials with binary data can use a variety of statistical methods. Zero-event trials may create analytic problems. We explored how different methods may impact inferences from meta-analyses containing zero-event trials.

Originalsprog	Engelsk
Tidsskrift	American Journal of Gastroenterology
Vol/bind	104
Udgave nummer	3
Sider (fra-til)	546-51
Antal sider	6
ISSN	0002-9270
DOI	https://doi.org/10.1038/ajg.2008.22
Status	Udgivet - mar. 2009

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10.1038/ajg.2008.22

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title = "Robustness assessments are needed to reduce bias in meta-analyses that include zero-event randomized trials",

abstract = "Meta-analysis of randomized trials with binary data can use a variety of statistical methods. Zero-event trials may create analytic problems. We explored how different methods may impact inferences from meta-analyses containing zero-event trials.",

keywords = "Bias (Epidemiology), Data Interpretation, Statistical, Meta-Analysis as Topic, Randomized Controlled Trials as Topic",

author = "F Keus and J Wetterslev and C Gluud and Gooszen, \{H G\} and \{van Laarhoven\}, \{C J H M\}",

year = "2009",

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AU - van Laarhoven, C J H M

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KW - Bias (Epidemiology)

KW - Data Interpretation, Statistical

KW - Meta-Analysis as Topic

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Robustness assessments are needed to reduce bias in meta-analyses that include zero-event randomized trials

Abstract

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