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Risk of adhesive bowel obstruction after abdominal surgery. A national cohort study of 665,423 Danish women

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@article{a295b756c39f453ba5e5035dbf435d59,
title = "Risk of adhesive bowel obstruction after abdominal surgery. A national cohort study of 665,423 Danish women",
abstract = "BACKGROUND: Adhesive bowel obstruction is associated with considerable morbidity and mortality, but the magnitude of the risk is debated.METHOD: In a national cohort of all Danish women with an abdominal operation (N = 665,423) between 1977 and 2013, the risk of adhesive bowel obstruction was assessed by Cox multiple regression. Covariates were the number of abdominal operations, the surgical methods, the anatomical site involved, and the calendar year.RESULTS: In the cohort, 1.4{\%} experienced an episode of adhesive bowel obstruction. The risk increased 33-43{\%} during the study period, was lower after gynecological and obstetrical procedures compared to gastrointestinal (HR 0.36 [0.34-0.38]), lower after laparoscopic compared to laparotomic surgery (HR 0.51 [0.48-0.54]) and increased proportionally after each additional operation.CONCLUSIONS: The risk of adhesive bowel obstruction after abdominal operations depends on the site of earlier operations, the method of access and the number of earlier operations.",
keywords = "Adhesions, Adhesive bowel obstruction, Cohort study, Surgery",
author = "Christina Norrbom and Marianne Steding-Jessen and Agger, {Carsten Thye} and Merete Osler and Marie Krabbe-Sorensen and Annette Settnes and Lisbeth Nilas and Loekkegaard, {Ellen Christine Leth}",
note = "Copyright {\circledC} 2018 Elsevier Inc. All rights reserved.",
year = "2019",
month = "4",
day = "1",
doi = "10.1016/j.amjsurg.2018.10.035",
language = "English",
volume = "217",
pages = "694--703",
journal = "American Journal of Surgery",
issn = "0002-9610",
publisher = "Elsevier Inc",
number = "4",

}

RIS

TY - JOUR

T1 - Risk of adhesive bowel obstruction after abdominal surgery. A national cohort study of 665,423 Danish women

AU - Norrbom, Christina

AU - Steding-Jessen, Marianne

AU - Agger, Carsten Thye

AU - Osler, Merete

AU - Krabbe-Sorensen, Marie

AU - Settnes, Annette

AU - Nilas, Lisbeth

AU - Loekkegaard, Ellen Christine Leth

N1 - Copyright © 2018 Elsevier Inc. All rights reserved.

PY - 2019/4/1

Y1 - 2019/4/1

N2 - BACKGROUND: Adhesive bowel obstruction is associated with considerable morbidity and mortality, but the magnitude of the risk is debated.METHOD: In a national cohort of all Danish women with an abdominal operation (N = 665,423) between 1977 and 2013, the risk of adhesive bowel obstruction was assessed by Cox multiple regression. Covariates were the number of abdominal operations, the surgical methods, the anatomical site involved, and the calendar year.RESULTS: In the cohort, 1.4% experienced an episode of adhesive bowel obstruction. The risk increased 33-43% during the study period, was lower after gynecological and obstetrical procedures compared to gastrointestinal (HR 0.36 [0.34-0.38]), lower after laparoscopic compared to laparotomic surgery (HR 0.51 [0.48-0.54]) and increased proportionally after each additional operation.CONCLUSIONS: The risk of adhesive bowel obstruction after abdominal operations depends on the site of earlier operations, the method of access and the number of earlier operations.

AB - BACKGROUND: Adhesive bowel obstruction is associated with considerable morbidity and mortality, but the magnitude of the risk is debated.METHOD: In a national cohort of all Danish women with an abdominal operation (N = 665,423) between 1977 and 2013, the risk of adhesive bowel obstruction was assessed by Cox multiple regression. Covariates were the number of abdominal operations, the surgical methods, the anatomical site involved, and the calendar year.RESULTS: In the cohort, 1.4% experienced an episode of adhesive bowel obstruction. The risk increased 33-43% during the study period, was lower after gynecological and obstetrical procedures compared to gastrointestinal (HR 0.36 [0.34-0.38]), lower after laparoscopic compared to laparotomic surgery (HR 0.51 [0.48-0.54]) and increased proportionally after each additional operation.CONCLUSIONS: The risk of adhesive bowel obstruction after abdominal operations depends on the site of earlier operations, the method of access and the number of earlier operations.

KW - Adhesions

KW - Adhesive bowel obstruction

KW - Cohort study

KW - Surgery

UR - http://www.scopus.com/inward/record.url?scp=85056300904&partnerID=8YFLogxK

U2 - 10.1016/j.amjsurg.2018.10.035

DO - 10.1016/j.amjsurg.2018.10.035

M3 - Journal article

VL - 217

SP - 694

EP - 703

JO - American Journal of Surgery

JF - American Journal of Surgery

SN - 0002-9610

IS - 4

ER -

ID: 55617944