Risk markers of late high-degree atrioventricular block in patients with left ventricular dysfunction after an acute myocardial infarction: a CARISMA substudy

Uffe Jakob Ortved Gang, Christian Jøns, Rikke Mørch Jørgensen, Steen Zabell Abildstrøm, Marc D Messier, Jens Haarbo, Heikki V Huikuri, Poul Erik Bloch Thomsen, on behalf of the CARISMA investigators

26 Citationer (Scopus)

Abstract

Aims High-degree atrioventricular block (HAVB) after acute myocardial infarction (AMI) is associated with increased risk of mortality. Risk markers and predictors of HAVB occurring after AMI are largely unknown. The aim of this study was to assess the predictive value of risk markers derived from a series of non-invasive and invasive tests for the development of HAVB documented by an implantable loop recorder (ILR) in late convalescent phases of an AMI. Methods and results The study included 292 patients with AMI and subsequent left ventricular dysfunction without prior HAVB or implanted pacemaker. An ILR was implanted for continuous arrhythmia surveillance. Risk stratification testing was performed at inclusion and 6 weeks after AMI. The tests included echocardiography, electrocardiogram (ECG), 24 h Holter monitoring, and an invasive electrophysiological study. High-degree atrioventricular block was documented in 28 (10%) patients during a median follow-up of 2.0 (0.4-2.0) years. Heart rate variability (HRV) measures and non-sustained ventricular tachycardia occurring at the week 6 Holter monitoring were highly predictive of HAVB. Power law slope
OriginalsprogEngelsk
TidsskriftEuropace
Vol/bind13
Udgave nummer10
Sider (fra-til)1471-1477
ISSN1099-5129
DOI
StatusUdgivet - 10 jun. 2011

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