Risk Factors for Premature Death in Diabetes Patients who Undergo Amputations below Ankle Level

Therese E Wilbek, Rasmus B Jansen, Bo Jørgensen, Ole Lander Svendsen

4 Citationer (Scopus)

Abstract

AIM: To identify risk factors for early death in diabetes patients who undergo amputations below the ankle.

METHODS: A retrospective study, where all hospital records of all diabetes patients who had undergone minimum one amputation below the ankle at the CWHC Bispebjerg Hospital, Denmark, in the period 1996-2013, were examined. The amputations were mainly trans-metatarsal amputations and partial amputations of toes. The participants were found via ICD10-codes. The included patients were followed from their first contact to the last registered contact. The statistical analysis in this article is performed on patients with a of minimum 5-year follow-up.

RESULTS: The 5 year mortality was 42% for patients with type 2 diabetes, and 29% for patients with type 1 diabetes. For patients with type 2 diabetes, multivariable analysis showed that high age, peripheral arterial insufficiency and short time from first admission to amputation were independently statistically significantly associated with increased 5-years mortality. Use of statins was associated with decreased mortality. 35% died as a result of their diabetes, mostly due to cardiovascular causes.

CONCLUSION: Short time from first admission to amputation is a risk factor for early death. Arterial insufficiency and high age is also associated with increased mortality, whereas use of statin is associated with decreased mortality, in patients with type 2 diabetes.

OriginalsprogTysk
TidsskriftExperimental and Clinical Endocrinology and Diabetes
Vol/bind126
Udgave nummer1
Sider (fra-til)61-65
Antal sider5
ISSN0947-7349
DOI
StatusUdgivet - jan. 2018

Emneord

  • Adult
  • Aged
  • Amputation/statistics & numerical data
  • Denmark/epidemiology
  • Diabetes Mellitus, Type 1/mortality
  • Diabetes Mellitus, Type 2/mortality
  • Diabetic Foot/surgery
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Mortality, Premature
  • Risk Factors

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