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Reversible audiometric threshold changes in children with uncomplicated malaria

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

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  3. Traffic flow and microbial air contamination in operating rooms at a major teaching hospital in Ghana

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Vis graf over relationer
Background. Plasmodium falciparum malaria, as well as certain antimalarial drugs, is associated with hearing impairment in adults. There is little information, however, on the extent, if any, of this effect in children, and the evidence linking artemisinin combination therapies (ACTs) with hearing is inconclusive. Methods. Audiometry was conducted in children with uncomplicated malaria treated with artesunate-amodiaquine (n = 37), artemether-lumefantrine (n = 35), or amodiaquine (n = 8) in Accra, Ghana. Audiometry was repeated 3, 7, and 28 days later and after 9 months. Audiometric thresholds were compared with those of a control group of children (n = 57) from the same area. Findings. During the acute stage, hearing threshold levels of treated children were significantly elevated compared with controls (P
OriginalsprogEngelsk
TidsskriftJournal of Tropical Medicine
Vol/bind2013
Sider (fra-til)360540
ISSN1687-9686
DOI
StatusUdgivet - 7 mar. 2013

ID: 42497724