Restless legs syndrome og depression

Johannes Rasmussen, Poul Videbech

1 Citationer (Scopus)


Epidemiological studies report an odds ratio of 2-4 for major depression among patients with restless legs syndrome (RLS) compared with healthy controls. Also a high prevalence of RLS in populations of depressed patients is seen. Several possible explanations are proposed, such as dopamine dysfunction, sleep disturbances, shared diagnostic criteria and adverse effects of antidepressive treatment. There is a low degree of evidence for a treatment strategy when depression and RLS coexist. Furthermore, it is important to realize, that some antidepressants can induce or worsen RLS.

Bidragets oversatte titelRestless legs syndrome and depression
TidsskriftUgeskrift for Laeger
Udgave nummer35
Sider (fra-til)2113-7
Antal sider5
StatusUdgivet - 29 aug. 2011
Udgivet eksterntJa


  • Antidepressive Agents/adverse effects
  • Depressive Disorder, Major/complications
  • Dopamine Agonists/adverse effects
  • Dopamine Antagonists/adverse effects
  • Evidence-Based Medicine
  • Humans
  • Polysomnography
  • Restless Legs Syndrome/chemically induced


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